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Cellosaurus CHO E-10C101-250 (CVCL_3711)

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Cell line name CHO E-10C101-250
Synonyms E-10C101-250; HIIF-D; R10C101-250nM; R10C101-250 nM
Accession CVCL_3711
Resource Identification Initiative To cite this cell line use: CHO E-10C101-250 (RRID:CVCL_3711)
Comments Group: Patented cell line.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-8200.
Selected for resistance to: ChEBI; CHEBI_44185; Methotrexate (MTX).
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:5438; IFNG.
Genetic integration: Method=Transfection; Gene=MGI; MGI:94890; Dhfr.
Transformant: ChEBI; CHEBI_23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE).
Transformant: NCIt; C44386; Gamma radiation.
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Cell type: Epithelial cell of ovary; CL=CL_2000064.
Sequence variations
  • Gene deletion; UniProtKB; Q2MH30; Dhfr; Zygosity=Heterozygous (from parent cell line).
  • Mutation; UniProtKB; Q2MH30; Dhfr; Simple; p.Thr137Arg (c.410G>C); Zygosity=Heterozygous (from parent cell line).
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_E4HN (CHO E-10C)
Children:
CVCL_VT63 (CHO IM4)
Sex of cell Female
Age at sampling Adult
Category Transformed cell line
Publications

Patent=EP0088540A2
Walter Charles Fiers;
DNA sequences, recombinant DNA molecules and processes for producing human immune interferon-like polypeptides.
Patent number EP0088540A2, 14-Sep-1983

Patent=US5004689
Walter Charles Fiers, Bernard Allet;
DNA sequences, recombinant DNA molecules and processes for producing human gamma interferon-like polypeptides in high yields.
Patent number US5004689, 02-Apr-1991

Cross-references
Cell line collections (Providers) ATCC; CRL-8200
Cell line databases/resources CLO; CLO_0003754
Encyclopedic resources Wikidata; Q54889543
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number12