ID   CHO E-10C101-250
AC   CVCL_3711
SY   E-10C101-250; HIIF-D; R10C101-250nM; R10C101-250 nM
DR   CLO; CLO_0003754
DR   ATCC; CRL-8200
DR   Wikidata; Q54889543
RX   Patent=EP0088540A2;
RX   Patent=US5004689;
CC   Group: Patented cell line.
CC   Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-8200.
CC   Selected for resistance to: ChEBI; CHEBI_44185; Methotrexate (MTX).
CC   Sequence variation: Gene deletion; UniProtKB; Q2MH30; Dhfr; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; UniProtKB; Q2MH30; Dhfr; Simple; p.Thr137Arg (c.410G>C); Zygosity=Heterozygous (from parent cell line).
CC   Genetic integration: Method=Transfection; Gene=HGNC; HGNC:5438; IFNG.
CC   Genetic integration: Method=Transfection; Gene=MGI; MGI:94890; Dhfr.
CC   Transformant: ChEBI; CHEBI_23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE).
CC   Transformant: NCIt; C44386; Gamma radiation.
CC   Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
CC   Cell type: Epithelial cell of ovary; CL=CL_2000064.
OX   NCBI_TaxID=10029; ! Cricetulus griseus (Chinese hamster)
HI   CVCL_E4HN ! CHO E-10C
SX   Female
AG   Adult
CA   Transformed cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 12
//
RX   Patent=EP0088540A2;
RA   Fiers W.C.;
RT   "DNA sequences, recombinant DNA molecules and processes for producing
RT   human immune interferon-like polypeptides.";
RL   Patent number EP0088540A2, 14-Sep-1983.
//
RX   Patent=US5004689;
RA   Fiers W.C., Allet B.;
RT   "DNA sequences, recombinant DNA molecules and processes for producing
RT   human gamma interferon-like polypeptides in high yields.";
RL   Patent number US5004689, 02-Apr-1991.
//