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Cellosaurus TF-1a (CVCL_3608)

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Cell line name TF-1a
Accession CVCL_3608
Resource Identification Initiative To cite this cell line use: TF-1a (RRID:CVCL_3608)
Comments Population: Japanese.
Characteristics: Growth factor independent clone of TF-1.
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Sequence variations
  • Gene fusion; HGNC; HGNC:15868; ABHD12 + HGNC; HGNC:1537; CBFA2T3; Name(s)=CBFA2T3-ABHD12 (from parent cell line).
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Pro (c.182A>C); ClinVar=VCV000280409; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Ile251Thrfs*94 (c.752delT); ClinVar=VCV001759367; Zygosity=Unspecified (from parent cell line).
Disease Erythroleukemia (NCIt: C7152)
Acute erythroid leukemia (ORDO: Orphanet_318)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0559 (TF-1)
Sex of cell Male
Age at sampling 35Y
Category Cancer cell line
STR profile Source(s): ATCC=CRL-2451

Markers:
AmelogeninX,Y
CSF1PO13
D2S133819
D3S135815
D5S81813
D7S82012
D8S117911,15
D13S3178,9
D16S5399,12
D18S5113
D19S43314,16
D21S1130
FGA18,19
Penta D10,13
Penta E5,17
TH017,9
TPOX8
vWA15,17

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Publications

PubMed=9716013; DOI=10.1016/S0145-2126(98)00073-3
Xiao-Tang Hu, Lynn C. Moscinski, Bobbye J. Hill, Quan-Lu Chen, Jie Wu, Ariana Brown Fisher, Kenneth S. Zuckerman;
Characterization of a unique factor-independent variant derived from human factor-dependent TF-1 cells: a transformed event.
Leuk. Res. 22:817-826(1998)

Cross-references
Cell line collections (Providers) ATCC; CRL-2451
BCRC; 60440
Cell line databases/resources CLO; CLO_0009328
cancercelllines; CVCL_3608
LINCS_LDP; LCL-1079
Biological sample resources BioSample; SAMN03471582
Encyclopedic resources Wikidata; Q54972201
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number25