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Cellosaurus SV7tert (CVCL_3602)

[Text version]
Cell line name SV7tert
Synonyms SV7 tert
Accession CVCL_3602
Resource Identification Initiative To cite this cell line use: SV7tert (RRID:CVCL_3602)
Comments Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=pSVori-).
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Disease Kidney angiomyolipoma (NCIt: C3888)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_J654 (SV7)
Children:
CVCL_0F39 (SV7tert PDGF)
Sex of cell Female
Age at sampling 63Y
Category Transformed cell line
STR profile Source(s): ATCC=CRL-2461

Markers:
AmelogeninX
CSF1PO10,12
D5S81811,13
D7S82011
D13S3178
D16S5399,11
TH016,9.3
TPOX8,11
vWA17,18

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Publications

PubMed=11485907; DOI=10.1016/S0002-9440(10)61720-8; PMCID=PMC1850536
Jack Leonard Arbiser, Raymond S.W. Yeung, Sharon Wheelan Weiss, Zoya K. Arbiser, Mahul B. Amin, Cynthia Cohen, David A. Frank, Sudipta Mahajan, Gordon Scott Herron, Ji-Wei Yang, Hiroki Onda ...Show all 20 authors... , H.B. Zhang, Xian-He Bai, Erik Janos Uhlmann, Allison Loehr, Hope Northrup, Paul Au, Ian J. Davis, David Erich Fisher, David Hillel Gutmann; Show fewer authors
The generation and characterization of a cell line derived from a sporadic renal angiomyolipoma: use of telomerase to obtain stable populations of cells from benign neoplasms.
Am. J. Pathol. 159:483-491(2001)

PubMed=15509531; DOI=10.1016/S0002-9440(10)63418-9; PMCID=PMC1618658
Xiao-Jun Lu, Jack Leonard Arbiser, James West, Marloes Hoedt-Miller, Alison Sheridan, Baskaran Govindarajan, Julie Wright Harral, David M. Rodman, Brian Fouty;
Tumor necrosis factor-related apoptosis-inducing ligand can induce apoptosis in subsets of premalignant cells.
Am. J. Pathol. 165:1613-1620(2004)

PubMed=15695519; DOI=10.1074/jbc.M500411200
Baskaran Govindarajan, Asha Shah, Cynthia Cohen, Rebecca S. Arnold, Jeffrey Scot Schechner, Jun Chung, Arthur M. Mercurio, Rhoda M. Alani, Byungwoo Ryu, Chun-Yang Fan, Jose Manuel Cuezva ...Show all 13 authors... , Marta Martinez, Jack Leonard Arbiser; Show fewer authors
Malignant transformation of human cells by constitutive expression of platelet-derived growth factor-BB.
J. Biol. Chem. 280:13936-13943(2005)

PubMed=17592550; DOI=10.2119/2006-00070.Lim; PMCID=PMC1892760
So Dug Lim, William B. Stallcup, Benjamin Lefkove, Baskaran Govindarajan, Kit Sing Au, Hope Northrup, Deborah Lang, David Erich Fisher, Avani Patel, Mahul B. Amin, Jack Leonard Arbiser;
Expression of the neural stem cell markers NG2 and L1 in human angiomyolipoma: are angiomyolipomas neoplasms of stem cells?
Mol. Med. 13:160-165(2007)

Cross-references
Cell line collections (Providers) ATCC; CRL-2461 - Discontinued
Cell line databases/resources CLO; CLO_0009171
Anatomy/cell type resources BTO; BTO_0004390
Biological sample resources BioSample; SAMN03471581
Encyclopedic resources Wikidata; Q54970982
Polymorphism and mutation databases Cosmic; 2777739
Entry history
Entry creation04-Apr-2012
Last entry update14-Aug-2025
Version number23