ID   SV7tert
AC   CVCL_3602
SY   SV7 tert
DR   BTO; BTO_0004390
DR   CLO; CLO_0009171
DR   ATCC; CRL-2461
DR   BioSample; SAMN03471581
DR   Cosmic; 2777739
DR   Wikidata; Q54970982
RX   PubMed=11485907;
RX   PubMed=15509531;
RX   PubMed=15695519;
RX   PubMed=17592550;
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; SV40 large T antigen.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=pSVori-).
CC   Discontinued: ATCC; CRL-2461; true.
CC   Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
ST   Source(s): ATCC=CRL-2461
ST   Amelogenin: X
ST   CSF1PO: 10,12
ST   D13S317: 8
ST   D16S539: 9,11
ST   D5S818: 11,13
ST   D7S820: 11
ST   TH01: 6,9.3
ST   TPOX: 8,11
ST   vWA: 17,18
DI   NCIt; C3888; Kidney angiomyolipoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_J654 ! SV7
SX   Female
AG   63Y
CA   Transformed cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 22
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RX   PubMed=11485907; DOI=10.1016/S0002-9440(10)61720-8; PMCID=PMC1850536;
RA   Arbiser J.L., Yeung R.S.W., Weiss S.W., Arbiser Z.K., Amin M.B., Cohen C.,
RA   Frank D.A., Mahajan S., Herron G.S., Yang J.-W., Onda H., Zhang H.B.,
RA   Bai X.-H., Uhlmann E.J., Loehr A., Northrup H., Au P., Davis I.J.,
RA   Fisher D.E., Gutmann D.H.;
RT   "The generation and characterization of a cell line derived from a
RT   sporadic renal angiomyolipoma: use of telomerase to obtain stable
RT   populations of cells from benign neoplasms.";
RL   Am. J. Pathol. 159:483-491(2001).
//
RX   PubMed=15509531; DOI=10.1016/S0002-9440(10)63418-9; PMCID=PMC1618658;
RA   Lu X.-J., Arbiser J.L., West J., Hoedt-Miller M., Sheridan A.,
RA   Govindarajan B., Harral J.W., Rodman D.M., Fouty B.;
RT   "Tumor necrosis factor-related apoptosis-inducing ligand can induce
RT   apoptosis in subsets of premalignant cells.";
RL   Am. J. Pathol. 165:1613-1620(2004).
//
RX   PubMed=15695519; DOI=10.1074/jbc.M500411200;
RA   Govindarajan B., Shah A., Cohen C., Arnold R.S., Schechner J.S., Chung J.,
RA   Mercurio A.M., Alani R.M., Ryu B., Fan C.-Y., Cuezva J.M., Martinez M.,
RA   Arbiser J.L.;
RT   "Malignant transformation of human cells by constitutive expression of
RT   platelet-derived growth factor-BB.";
RL   J. Biol. Chem. 280:13936-13943(2005).
//
RX   PubMed=17592550; DOI=10.2119/2006-00070.Lim; PMCID=PMC1892760;
RA   Lim S.D., Stallcup W.B., Lefkove B., Govindarajan B., Au K.S.,
RA   Northrup H., Lang D., Fisher D.E., Patel A., Amin M.B., Arbiser J.L.;
RT   "Expression of the neural stem cell markers NG2 and L1 in human
RT   angiomyolipoma: are angiomyolipomas neoplasms of stem cells?";
RL   Mol. Med. 13:160-165(2007).
//