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Cellosaurus 143B pML BK TK (CVCL_3477)

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Cell line name 143B pML BK TK
Synonyms 143B PML BK TK
Accession CVCL_3477
Resource Identification Initiative To cite this cell line use: 143B pML BK TK (RRID:CVCL_3477)
Comments Group: Patented cell line.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-8304.
Population: Caucasian.
Derived from site: In situ; Bone, right femur; UBERON=UBERON_0000981.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Ser (c.34G>A); ClinVar=VCV000012584; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Ala59Thr (c.175G>A); ClinVar=VCV000012581; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg156Pro (c.467G>C); ClinVar=VCV000634768; Zygosity=Homozygous (from parent cell line).
Disease Osteosarcoma (NCIt: C9145)
Osteosarcoma (ORDO: Orphanet_668)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2270 (143B)
Sex of cell Female
Age at sampling 13Y
Category Cancer cell line
STR profile Source(s): ATCC=CRL-8304

Markers:
AmelogeninX
CSF1PO12
D2S133824,25
D3S135815
D5S81813
D7S82011,12
D8S117911,14
D13S31712
D16S53910,13
D18S5117
D19S43313
D21S1131.2,32.2
FGA24
Penta D9,10
Penta E7,12
TH016
TPOX11
vWA18

Run an STR similarity search on this cell line
Publications

Patent=US4562155
Robert P. Ricciardi, Giuseppe Barbanti-Brodano, Gabriele Milanesi;
Hybrid viral plasmid and microorganisms containing same.
Patent number US4562155, 31-Dec-1985

Cross-references
Cell line collections (Providers) ATCC; CRL-8304
Cell line databases/resources CLO; CLO_0001089
cancercelllines; CVCL_3477
LINCS_LDP; LCL-1418
Encyclopedic resources Wikidata; Q54581908
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number25