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Cellosaurus 143.98.2 (CVCL_3476)

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Cell line name 143.98.2
Accession CVCL_3476
Resource Identification Initiative To cite this cell line use: 143.98.2 (RRID:CVCL_3476)
Comments Group: Patented cell line.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-11226.
Population: Caucasian.
Derived from site: In situ; Bone, right femur; UBERON=UBERON_0000981.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Ser (c.34G>A); ClinVar=VCV000012584; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Ala59Thr (c.175G>A); ClinVar=VCV000012581; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg156Pro (c.467G>C); ClinVar=VCV000634768; Zygosity=Homozygous (from parent cell line).
Disease Osteosarcoma (NCIt: C9145)
Osteosarcoma (ORDO: Orphanet_668)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2270 (143B)
Sex of cell Female
Age at sampling 13Y
Category Cancer cell line
STR profile Source(s): ATCC=CRL-11226

Markers:
AmelogeninX
CSF1PO12
D5S81813
D7S82011,12
D13S31712
D16S53910,13
TH016
TPOX11
vWA18

Run an STR similarity search on this cell line
Publications

Patent=US5543297
Wanda A. Cromlish, Brian P. Kennedy, Gary O'Neill, Philip J. Vickers, Elizabeth Wong, Joseph A. Mancini;
Human cyclooxygenase-2 cDNA and assays for evaluating cyclooxygenase-2 activity.
Patent number US5543297, 06-Aug-1996

Cross-references
Cell line collections (Providers) ATCC; CRL-11226 - Discontinued
Cell line databases/resources CLO; CLO_0001085
cancercelllines; CVCL_3476
Encyclopedic resources Wikidata; Q54581811
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number22