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Cellosaurus PLHC-1 (CVCL_3466)

[Text version]
Cell line name PLHC-1
Synonyms Poeciliopsis Lucida Hepatocellular Carcinoma-1; PLHC-1/wt; PLHC1
Accession CVCL_3466
Resource Identification Initiative To cite this cell line use: PLHC-1 (RRID:CVCL_3466)
Comments Group: Fish cell line.
Transformant: ChEBI; CHEBI_254496; 7,12-dimethyltetraphene (DMBA; dimethylbenzanthracene).
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Disease Poeciliopsis lucida hepatocellular carcinoma (NCIt: C134962)
Species of origin Poeciliopsis lucida (Desert topminnow) (NCBI Taxonomy: 56613)
Hierarchy Children:
CVCL_S585 (PLHC-1/dox)
Sex of cell Female
Age at sampling Adult
Category Cancer cell line
Publications

PubMed=1868789; DOI=10.1016/0147-6513(91)90072-W
Harvey Jerome Babich, Daniel W. Rosenberg, Ellen Borenfreund;
In vitro cytotoxicity studies with the fish hepatoma cell line, PLHC-1 (Poeciliopsis lucida).
Ecotoxicol. Environ. Saf. 21:327-336(1991)

PubMed=9734273; DOI=10.1016/S0045-6535(97)10248-X
Sirpa E. Huuskonen, Mark E. Hahn, Pirjo Lindstrom-Seppa;
A fish hepatoma cell line (PLHC-1) as a tool to study cytotoxicity and CYP1A induction properties of cellulose and wood chip extracts.
Chemosphere 36:2921-2932(1998)

DOI=10.1016/S1873-0140(05)80005-0
Niels C. Bols, Vivian R. Dayeh, Lucy E.J. Lee, Kristin Schirmer;
Use of fish cell lines in the toxicology and ecotoxicology of fish Piscine cell lines in environmental toxicology.
(In book chapter) Biochemistry and molecular biology of fishes, Vol. 6; Mommsen, Thomas P. & Moon, Thomas W. (eds.); pp.43-84; Elsevier; Amsterdam; Netherlands (2005)

PubMed=21392495; DOI=10.1016/j.aquatox.2011.02.005
Roko Zaja, Jovica Loncar, Marta Popovic, Tvrtko Smital;
First characterization of fish P-glycoprotein (abcb1) substrate specificity using determinations of its ATPase activity and calcein-AM assay with PLHC-1/dox cell line.
Aquat. Toxicol. 103:53-62(2011)

PubMed=22281180; DOI=10.1016/j.tiv.2012.01.001
Aude Kienzler, Xavier Tronchere, Alain Devaux, Sylvie Bony;
Assessment of RTG-W1, RTL-W1, and PLHC-1 fish cell lines for genotoxicity testing of environmental pollutants by means of a Fpg-modified comet assay.
Toxicol. In Vitro 26:500-510(2012)

DOI=10.3390/fishes7060354
Cristobal Espinosa-Ruiz, Javier Mayor-Lafuente, Maria Angeles Esteban;
Mitochondrial metabolism characterization of four different fish cell lines.
Fishes 7:354.1-354.6(2022)

Cross-references
Cell line collections (Providers) ATCC; CRL-2406
Cell line databases/resources CLO; CLO_0008460
Anatomy/cell type resources BTO; BTO_0002331
Encyclopedic resources Wikidata; Q54947578
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number21