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Cellosaurus OCUG-1 (CVCL_3083)

[Text version]
Cell line name OCUG-1
Synonyms OCUG1; Osaka City University Gallbladder-1
Accession CVCL_3083
Resource Identification Initiative To cite this cell line use: OCUG-1 (RRID:CVCL_3083)
Comments Part of: Biliary tract cancer cell line atlas.
Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Population: Japanese.
Doubling time: 47.1 hours (PubMed=21533512).
Omics: Transcriptomics; RNAseq.
Omics: Variations; SNP array analysis.
Derived from site: Metastatic; Peritoneal effusion; UBERON=UBERON_0001268.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg267Trp (c.799C>T); ClinVar=VCV000141764; Zygosity=Heterozygous (DepMap=ACH-001619).
Disease Gallbladder carcinoma (NCIt: C3844)
Carcinoma of gallbladder and extrahepatic biliary tract (ORDO: Orphanet_56044)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_XD21 (OCUG-1-Luc#5)
Sex of cell Male
Age at sampling 43Y
Category Cancer cell line
STR profile Source(s): DepMap=ACH-001619; JCRB=JCRB0191

Markers:
AmelogeninX
CSF1PO10,12
D3S135815
D5S81810,12
D7S82010,11
D8S117914,15
D13S3178,11
D16S5399,13
D18S5116,19
D21S1128,29
FGA21,24
Penta D9
Penta E5,20
TH017,9.3
TPOX8,11
vWA15,16 (JCRB=JCRB0191)
16 (DepMap=ACH-001619)

Run an STR similarity search on this cell line
Publications

PubMed=21533512; DOI=10.3892/ijo.10.6.1251
Nobuya Yamada, Yong-Suk Chung, Hiroshi Ohtani, Teruyoshi Ikeda, Naoyoshi Onoda, Tetsuji Sawada, Yukio Nishiguchi, Tadayoshi Hasuma, Michio Sowa;
Establishment and characterization of a new human gallbladder carcinoma cell line (OCUG-1) producing TA-4.
Int. J. Oncol. 10:1251-1255(1997)

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662
S. Michael Rothenberg, Gayatry Mohapatra, Miguel N. Rivera, Daniel Winokur, Patricia Greninger, Mai Nitta, Peter M. Sadow, Gaya Sooriyakumar, Brian W. Brannigan, Matthew J. Ulman, Rushika M. Perera ...Show all 22 authors... , Rui Wang, Angela Tam, Xiao-Jun Ma, Mark Erlander, Dennis C. Sgroi, James W. Rocco, Mark W. Lingen, Ezra E.W. Cohen, David Neil Louis, Jeffrey Settleman, Daniel Arie Haber; Show fewer authors
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)

PubMed=32899426; DOI=10.3390/cancers12092510; PMCID=PMC7565451
Dominique Scherer, Marcela Davila-Lopez, Benjamin Goeppert, Sanna Abrahamsson, Rosa Gonzalez Silos, Igor Nova, Katherine Marcelain, Juan Carlos Roa, David Ibberson, Sinan U. Umu, Trine Ballestad Rounge ...Show all 13 authors... , Stephanie Roessler, Justo Lorenzo-Bermejo; Show fewer authors
RNA sequencing of hepatobiliary cancer cell lines: data and applications to mutational and transcriptomic profiling.
Cancers (Basel) 12:2510.1-2510.14(2020)

PubMed=39026794; DOI=10.1101/2024.07.04.601970; PMCID=PMC11257448
Vindhya Vijay, Negin Karisani, Lei Shi, Yu-Han Hung, Phuong Vu, Prabhat Kattel, Lauren Kenney, Joshua Merritt, Ramzi Adil, Qi-Biao Wu, Yuan-Li Zhen ...Show all 39 authors... , Robert Morris, Johannes Kreuzer, Meena Kathiresan, Xcanda Ixchel Herrera Lopez, Haley Ellis, Ilaria G. Gritti, Lilian Lecorgne, Ines Farag, Alexandra Popa, William Shen, Hiroyuki Kato, Qin Xu, Eranga Roshan Balasooriya, Meng-Ju Wu, Saireudee Chaturantabut, Robin Kate Kelley, James Mark Cleary, Michael Scott Lawrence, David E. Root, Cyril Henri Benes, Vikram Deshpande, Dejan Juric, William Raj Sellers, Cristina Rosa Ferrone, Wilhelm Haas, Francisca Vazquez, Gad Getz, Nabeel M. Bardeesy; Show fewer authors
Generation of a biliary tract cancer cell line atlas reveals molecular subtypes and therapeutic targets.
bioRxiv 2024:07.04.601970-07.04.601970(2024)

Cross-references
Cell line collections (Providers) JCRB; JCRB0191
Cell line databases/resources CLO; CLO_0009938
cancercelllines; CVCL_3083
Cell_Model_Passport; SIDM01842
DepMap; ACH-001619
LINCS_LDP; LCL-1800
Biological sample resources BioSample; SAMN03471651
Encyclopedic resources Wikidata; Q54931819
Gene expression databases GEO; GSM827176
Polymorphism and mutation databases Cosmic; 2629295
Cosmic; 2674062
Progenetix; CVCL_3083
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number27