ID   OCUG-1
AC   CVCL_3083
SY   OCUG1; Osaka City University Gallbladder-1
DR   CLO; CLO_0009938
DR   BioSample; SAMN03471651
DR   cancercelllines; CVCL_3083
DR   Cell_Model_Passport; SIDM01842
DR   Cosmic; 2629295
DR   Cosmic; 2674062
DR   DepMap; ACH-001619
DR   GEO; GSM827176
DR   JCRB; JCRB0191
DR   LINCS_LDP; LCL-1800
DR   Progenetix; CVCL_3083
DR   Wikidata; Q54931819
RX   PubMed=20215515;
RX   PubMed=21533512;
RX   PubMed=32899426;
RX   PubMed=39026794;
CC   Part of: Biliary tract cancer cell line atlas.
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Population: Japanese.
CC   Doubling time: 47.1 hours (PubMed=21533512).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg267Trp (c.799C>T); ClinVar=VCV000141764; Zygosity=Heterozygous (DepMap=ACH-001619).
CC   Omics: Transcriptomics; RNAseq.
CC   Omics: Variations; SNP array analysis.
CC   Derived from site: Metastatic; Peritoneal effusion; UBERON=UBERON_0001268.
ST   Source(s): DepMap=ACH-001619; JCRB=JCRB0191
ST   Amelogenin: X
ST   CSF1PO: 10,12
ST   D13S317: 8,11
ST   D16S539: 9,13
ST   D18S51: 16,19
ST   D21S11: 28,29
ST   D3S1358: 15
ST   D5S818: 10,12
ST   D7S820: 10,11
ST   D8S1179: 14,15
ST   FGA: 21,24
ST   Penta D: 9
ST   Penta E: 5,20
ST   TH01: 7,9.3
ST   TPOX: 8,11
ST   vWA: 15,16 (JCRB=JCRB0191)
ST   vWA: 16 (DepMap=ACH-001619)
DI   NCIt; C3844; Gallbladder carcinoma
DI   ORDO; Orphanet_56044; Carcinoma of gallbladder and extrahepatic biliary tract
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   43Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 27
//
RX   PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662;
RA   Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P.,
RA   Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J.,
RA   Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C.,
RA   Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J.,
RA   Haber D.A.;
RT   "A genome-wide screen for microdeletions reveals disruption of
RT   polarity complex genes in diverse human cancers.";
RL   Cancer Res. 70:2158-2164(2010).
//
RX   PubMed=21533512; DOI=10.3892/ijo.10.6.1251;
RA   Yamada N., Chung Y.-S., Ohtani H., Ikeda T., Onoda N., Sawada T.,
RA   Nishiguchi Y., Hasuma T., Sowa M.;
RT   "Establishment and characterization of a new human gallbladder
RT   carcinoma cell line (OCUG-1) producing TA-4.";
RL   Int. J. Oncol. 10:1251-1255(1997).
//
RX   PubMed=32899426; DOI=10.3390/cancers12092510; PMCID=PMC7565451;
RA   Scherer D., Davila-Lopez M., Goeppert B., Abrahamsson S.,
RA   Gonzalez Silos R., Nova I., Marcelain K., Roa J.C., Ibberson D.,
RA   Umu S.U., Rounge T.B., Roessler S., Lorenzo-Bermejo J.;
RT   "RNA sequencing of hepatobiliary cancer cell lines: data and
RT   applications to mutational and transcriptomic profiling.";
RL   Cancers (Basel) 12:2510.1-2510.14(2020).
//
RX   PubMed=39026794; DOI=10.1101/2024.07.04.601970; PMCID=PMC11257448;
RA   Vijay V., Karisani N., Shi L., Hung Y.-H., Vu P., Kattel P., Kenney L.,
RA   Merritt J., Adil R., Wu Q.-B., Zhen Y.-L., Morris R., Kreuzer J.,
RA   Kathiresan M., Herrera Lopez X.I., Ellis H., Gritti I.G., Lecorgne L.,
RA   Farag I., Popa A., Shen W., Kato H., Xu Q., Balasooriya E.R., Wu M.-J.,
RA   Chaturantabut S., Kelley R.K., Cleary J.M., Lawrence M.S., Root D.E.,
RA   Benes C.H., Deshpande V., Juric D., Sellers W.R., Ferrone C.R., Haas W.,
RA   Vazquez F., Getz G., Bardeesy N.M.;
RT   "Generation of a biliary tract cancer cell line atlas reveals
RT   molecular subtypes and therapeutic targets.";
RL   bioRxiv 2024:07.04.601970-07.04.601970(2024).
//