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Cellosaurus NOZ (CVCL_3079)

[Text version]
Cell line name NOZ
Synonyms NOZAWA; NOZC-1
Accession CVCL_3079
Resource Identification Initiative To cite this cell line use: NOZ (RRID:CVCL_3079)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Population: Japanese.
Doubling time: 40-48 hours (CelloPub=CLPUB00469); 30 hours (PubMed=32293552); 48 hours (PubMed=3154020); 30 hours (lot 09162008) (JCRB).
Omics: Deep exome analysis.
Omics: Transcriptome analysis by RNAseq.
Misspelling: NO2; Cosmic=2629294.
Sequence variations
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012583; Zygosity=Unspecified (DepMap).
  • Mutation; HGNC; 11998; TP53; Simple; p.Gln331Ter (c.991C>T); ClinVar=VCV000922893; Zygosity=Unspecified (DepMap).
Disease Gallbladder carcinoma (NCIt: C3844)
Carcinoma of gallbladder and extrahepatic biliary tract (ORDO: Orphanet_56044)
Derived from metastatic site: Ascites.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 48Y
Category Cancer cell line
STR profile Source(s): DepMap; JCRB

Penta D11,13
Penta E12,17

Run an STR similarity search on this cell line

Homma S.
Studies on the establishment and some biological characteristics of cultured human liver cancer cell lines. Their growth, functional and morphological characteristics and temperature sensitivities.
Jikeikai Med. J. 32:289-315(1985)

Homma S., Hasumura S., Nagamori S., Kameda H.
Establishment and characterization of a human gall bladder carcinoma cell line NOZ.
Hum. Cell 1:95-97(1988)

Hasumura S., Nagamori S., Fujise K., Homma S., Sujino H., Matsuura T., Shimizu K., Niiya M., Kameda H.
Combination therapy of hyperthermia and other methods in liver and bile tract cancers -- evaluation of these methods using cancer cell lines in vitro.
Gan To Kagaku Ryoho 16:1905-1912(1989)

Kawada M., Aizaki H., Fukaya K.-I., Niiya M., Matsuura T., Sujino H., Hasumura S., Nagamori S., Toda G.
Morphological changes in human gall bladder carcinoma cell line-NOZ due to epirubicin and doxorubicin.
Med. Electron Microsc. 27:175-177(1994)

PubMed=32293552; DOI=10.1186/s40659-020-00282-7
Garcia P., Bizama C., Rosa L., Espinoza J.A., Weber H., Cerda-Infante J., Sanchez M., Montecinos V.P., Lorenzo-Bermejo J., Boekstegers F., Davila-Lopez M., Alfaro F., Leiva-Acevedo C., Parra Z., Romero D., Kato S., Leal P., Lagos M., Roa J.C.
Functional and genomic characterization of three novel cell lines derived from a metastatic gallbladder cancer tumor.
Biol. Res. 53:13.1-13.17(2020)

PubMed=32899426; DOI=10.3390/cancers12092510
Scherer D., Davila Lopez M., Goeppert B., Abrahamsson S., Gonzalez Silos R., Nova I., Marcelain K., Roa J.C., Ibberson D., Umu S.U., Rounge T.B., Roessler S., Bermejo J.L.
RNA sequencing of hepatobiliary cancer cell lines: data and applications to mutational and transcriptomic profiling.
Cancers (Basel) 12:2510.1-2510.14(2020)

Cell line collections JCRB; JCRB1033
JCRB; NIHS0283 - Discontinued
Cell line databases/resources Cell_Model_Passport; SIDM01812
DepMap; ACH-001607
Biological sample resources BioSample; SAMN03472480
Encyclopedic resources Wikidata; Q54930937
Polymorphism and mutation databases Cosmic; 1122352
Cosmic; 2629294
Cosmic; 2674061
Entry history
Entry creation04-Apr-2012
Last entry update21-Mar-2023
Version number23