Cellosaurus logo
expasy logo

Cellosaurus U937-DC-SIGN (CVCL_2Z95)

[Text][XML][JSON]
Cell line name U937-DC-SIGN
Accession CVCL_2Z95
Resource Identification Initiative To cite this cell line use: U937-DC-SIGN (RRID:CVCL_2Z95)
Comments Population: Caucasian.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:1641; CD209.
Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene fusion; HGNC; HGNC:16063; MLLT10 + HGNC; HGNC:15514; PICALM; Name(s)=PICALM-MLLT10, CALM-AF10 (from parent cell line).
  • Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Gly129fs*51 (c.387_388insCGCC); Zygosity=Hemizygous (from parent cell line).
  • Mutation; HGNC; HGNC:9644; PTPN11; Simple; p.Gly60Arg (c.178G>C); ClinVar=VCV000372590; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; c.559+1G>A (p.Val173Trpfs*59); ClinVar=VCV000428908; Zygosity=Homozygous; Note=Splice donor mutation (from parent cell line).
  • Mutation; HGNC; HGNC:12796; WT1; Simple; p.Arg301Ter (c.901C>T) (p.Arg352Ter, c.1054C>T) (p.Arg374Ter, c.1120C>T); ClinVar=VCV000449416; Zygosity=Heterozygous (from parent cell line).
Disease Adult acute monocytic leukemia (NCIt: C8263)
Acute monoblastic/monocytic leukemia (ORDO: Orphanet_514)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0007 (U-937)
Sex of cell Male
Age at sampling 37Y
Category Cancer cell line
STR profile Source(s): ATCC=CRL-3253

Markers:
AmelogeninX
CSF1PO12
D5S81812
D7S8209,11
D13S31710,12
D16S53912
TH016,9.3
TPOX8,11
vWA14,15

Run an STR similarity search on this cell line
Publications

PubMed=17804661; DOI=10.1128/jcm.00827-07; PMCID=PMC2168473
Annette A. Kraus, William Messer, Laura B. Haymore, Aravinda M. de Silva;
Comparison of plaque- and flow cytometry-based methods for measuring dengue virus neutralization.
J. Clin. Microbiol. 45:3777-3780(2007)

Cross-references
Cell line collections (Providers) ATCC; CRL-3253
Cell line databases/resources cancercelllines; CVCL_2Z95
Encyclopedic resources Wikidata; Q54973776
Entry history
Entry creation22-Sep-2015
Last entry update19-Dec-2024
Version number16