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Cellosaurus DT40-INPP5D(-/-) (CVCL_2G93)

[Text version]

Cell line name DT40-INPP5D(-/-)
Synonyms SHIP^(-) DT40; SHIP-deficient DT40
Accession CVCL_2G93
Resource Identification Initiative To cite this cell line use: DT40-INPP5D(-/-) (RRID:CVCL_2G93)
Comments Group: Bird cell line.
Knockout cell: Method=Targeted integration; INPP5D.
Transformant: NCBI_TaxID; 11864; Avian leukosis virus (ALV).
Derived from sampling site: Cell type=B-cell.
Disease Chicken bursal lymphoma (NCIt: C134556)
Species of origin Gallus gallus (Chicken) (NCBI Taxonomy: 9031)
Breed/subspecies: Hy-Line SC.
Hierarchy Parent: CVCL_0249 (DT40)
Sex of cell Female
Age at sampling 1D
Category Cancer cell line

PubMed=9244303; DOI=10.1016/S0092-8674(00)80337-2
Ono M., Okada H., Bolland S., Yanagi S., Kurosaki T., Ravetch J.V.
Deletion of SHIP or SHP-1 reveals two distinct pathways for inhibitory signaling.
Cell 90:293-301(1997)

PubMed=9547347; DOI=10.1084/jem.187.8.1355
Maeda A., Kurosaki M., Ono M., Takai T., Kurosaki T.
Requirement of SH2-containing protein tyrosine phosphatases SHP-1 and SHP-2 for paired immunoglobulin-like receptor B (PIR-B)-mediated inhibitory signal.
J. Exp. Med. 187:1355-1360(1998)

Cell line collections RCB; RCB1465
Cell line databases/resources CLO; CLO_0051472
Encyclopedic resources Wikidata; Q54831486
Entry history
Entry creation22-Sep-2015
Last entry update17-Mar-2022
Version number8