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Cellosaurus KD [Human lip fibroblast] (CVCL_2970)

[Text version]
Cell line name KD [Human lip fibroblast]
Synonyms Karen Day
Accession CVCL_2970
Resource Identification Initiative To cite this cell line use: KD [Human lip fibroblast] (RRID:CVCL_2970)
Comments Population: Caucasian.
Senescence: Senesces at 38-40 PDL (JCRB=JCRB9103).
Doubling time: 51-70 hours (Note=Lot 06232003), ~27 hours (Note=Lot 11052009), ~36 hours (Note=Lot 12112017) (JCRB=JCRB9103).
Derived from site: In situ; Oral cavity, lip; UBERON=UBERON_0001833.
Cell type: Fibroblast; CL=CL_0000057.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
Sex of cell Female
Age at sampling 31Y
Category Finite cell line

Day R.S. III
Studies on repair of adenovirus 2 by human fibroblasts using normal, xeroderma pigmentosum, and xeroderma pigmentosum heterozygous strains.
Cancer Res. 34:1965-1970(1974)

PubMed=418410; DOI=10.1073/pnas.75.3.1334
Kakunaga T.
Neoplastic transformation of human diploid fibroblast cells by chemical carcinogens.
Proc. Natl. Acad. Sci. U.S.A. 75:1334-1338(1978)

PubMed=450131; DOI=10.1038/279797a0
Day R.S. III, Ziolkowski C.H.J.
Human brain tumour cell strains with deficient host-cell reactivation of N-methyl-N'-nitro-N-nitrosoguanidine-damaged adenovirus 5.
Nature 279:797-799(1979)

PubMed=22282976; DOI=10.1093/carcin/1.1.21
Day R.S. III, Ziolkowski C.H.J., Scudiero D.A., Meyer S.A., Mattern M.R.
Human tumor cell strains defective in the repair of alkylation damage.
Carcinogenesis 1:21-32(1980)

PubMed=6458814; DOI=10.1073/pnas.78.10.6451
Scudiero D.A., Meyer S.A., Clatterbuck B.E., Tarone R.E., Robbins J.H.
Hypersensitivity to N-methyl-N'-nitro-N-nitrosoguanidine in fibroblasts from patients with Huntington disease, familial dysautonomia, and other primary neuronal degenerations.
Proc. Natl. Acad. Sci. U.S.A. 78:6451-6455(1981)

PubMed=7301938; DOI=10.1111/j.1751-1097.1981.tb09049.x
Day R.S. III, Ziolkowski C.H.J., DiMattina M.
Decreased host cell reactivation of UV-irradiated adenovirus 5 by fibroblasts from Cockayne's syndrome patients.
Photochem. Photobiol. 34:603-607(1981)

PubMed=6622549; DOI=10.1111/j.1751-1097.1983.tb08373.x
Coohill T.P., Moore S.P., Grider R.A.
Action spectra (254-302 nm) for four human photosensitive cell lines.
Photochem. Photobiol. 38:105-107(1983)

PubMed=6621576; DOI=10.1016/0027-5107(83)90010-6
Tarone R.E., Scudiero D.A., Robbins J.H.
Statistical methods for in vitro cell survival assays.
Mutat. Res. 111:79-96(1983)

PubMed=3860870; DOI=10.1073/pnas.82.16.5400
Parshad R., Sanford K.K., Jones G.M.
Chromosomal radiosensitivity during the G2 cell-cycle period of skin fibroblasts from individuals with familial cancer.
Proc. Natl. Acad. Sci. U.S.A. 82:5400-5403(1985)

PubMed=3724780; DOI=10.1016/0167-8817(86)90043-x
Kantor G.J., Player A.N.
A further definition of characteristics of DNA-excision repair in xeroderma pigmentosum complementation group A strains.
Mutat. Res. 166:79-88(1986)

PubMed=2902939; DOI=10.1093/carcin/9.11.2073
McCormick J.J., Yang D.-J., Maher V.M., Farber R.A., Neuman W., Peterson W.D. Jr., Pollack M.S.
The HuT series of 'carcinogen-transformed' human fibroblast cell lines are derived from the human fibrosarcoma cell line 8387.
Carcinogenesis 9:2073-2079(1988)

PubMed=2463881; DOI=10.1093/carcin/10.2.265
Babich M.A., Day R.S. III
Synergistic killing of virus-transformed human cells with interferon and N-methyl-N'-nitro-N-nitrosoguanidine.
Carcinogenesis 10:265-268(1989)

Cell line collections (Providers) ATCC; CRL-1295 - Discontinued
Encyclopedic resources Wikidata; Q54899703
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number14