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Cellosaurus IM95m (CVCL_2962)

[Text version]
Cell line name IM95m
Synonyms IM95M; IM95 m; IM-95m
Accession CVCL_2962
Resource Identification Initiative To cite this cell line use: IM95m (RRID:CVCL_2962)
Comments Part of: MD Anderson Cell Lines Project.
Population: Japanese.
Characteristics: Compared to the parent cell line, it produces higher level of HGF, IL8 and VEGFA.
Doubling time: 29 hours (PubMed=29435981).
Omics: Genomics; Whole exome sequencing.
Omics: Proteomics; Expression; Reverse-phase protein array.
Omics: Transcriptomics; Microarray.
Omics: Transcriptomics; RNAseq.
Omics: Variations; Array-based CGH.
Omics: Variations; SNP array analysis.
Derived from site: In situ; Stomach; UBERON=UBERON_0000945.
HLA typing Source: PubMed=26589293
Class I
HLA-AA*26:03,26:03
HLA-BB*15:40,67:02
HLA-CC*12:02,12:02
Disease Gastric adenocarcinoma (NCIt: C4004)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2961 (IM95)
Sex of cell Male
Age at sampling 63Y
Category Cancer cell line
STR profile Source(s): JCRB=JCRB1075.1; PubMed=25877200

Markers:
AmelogeninX
CSF1PO11
D3S135814
D5S8189,11
D7S8209.3
D8S117912,13
D13S31710,12
D16S5399,10
D18S5113,23
D21S1131,32.2
FGA19,21
Penta D10,11
Penta E12
TH016,10
TPOX8,10
vWA17,18

Run an STR similarity search on this cell line
Web pages Info; MCLP; -; https://tcpaportal.org/mclp/
Publications

PubMed=14609362; DOI=10.1290/1543-706X(2003)039<0288:COACCH>2.0.CO;2
Mineko Iwai, Masahiko Matsuda, Yoshiaki Iwai;
Cloning of a cancer cell-producing hepatocyte growth factor, vascular endothelial growth factor, and interleukin-8 from gastric cancer cells.
In Vitro Cell. Dev. Biol. Anim. 39:288-290(2003)

PubMed=24807215; DOI=10.1038/ncomms4830; PMCID=PMC4024760
Jin-Feng Liu, Mark L. McCleland, Eric W. Stawiski, Florian Gnad, Oleg Mayba, Peter M. Haverty, Steffen Durinck, Ying-Jiun Chen, Christiaan Klijn, Suchit Jhunjhunwala, Michael Lawrence ...Show all 30 authors... , Han-Bin Liu, Yi-Nan Wan, Vivek S. Chopra, Murat Burat Yaylaoglu, Wen-Lin Yuan, Connie Ha, Houston N. Gilbert, Jens Reeder, Gregoire Pau, Jeremy Stinson, Howard M. Stern, Gerard Manning, Thomas D. Wu, Richard M. Neve, Frederic J. de Sauvage, Zora Modrusan, Somasekar Seshagiri, Ron Firestein, Ze-Min Zhang; Show fewer authors
Integrated exome and transcriptome sequencing reveals ZAK isoform usage in gastric cancer.
Nat. Commun. 5:3830.1-3830.8(2014)

PubMed=25343454; DOI=10.1371/journal.pone.0111146; PMCID=PMC4208810
Meng-Ling Choong, Shan-Ho Tan, Tuan-Zea Tan, Sravanthy Manesh, Anna Ngo, Jacklyn W.-Y. Yong, Henry He Yang, May Ann Lee;
Molecular integrative clustering of Asian gastric cell lines revealed two distinct chemosensitivity clusters.
PLoS ONE 9:e111146.1-e111146.9(2014)

PubMed=25485619; DOI=10.1038/nbt.3080
Christiaan Klijn, Steffen Durinck, Eric W. Stawiski, Peter M. Haverty, Zhao-Shi Jiang, Han-Bin Liu, Jeremiah Degenhardt, Oleg Mayba, Florian Gnad, Jin-Feng Liu, Gregoire Pau ...Show all 30 authors... , Jens Reeder, Yi Cao, Kiran Mukhyala, Suresh K. Selvaraj, Ma-Mie Yu, Gregory J. Zynda, Matthew J. Brauer, Thomas D. Wu, Robert Clifford Gentleman, Gerard Manning, Robert L. Yauch, Richard Bourgon, David Stokoe, Zora Modrusan, Richard M. Neve, Frederic J. de Sauvage, Jeffrey Settleman, Somasekar Seshagiri, Ze-Min Zhang; Show fewer authors
A comprehensive transcriptional portrait of human cancer cell lines.
Nat. Biotechnol. 33:306-312(2015)

PubMed=25877200; DOI=10.1038/nature14397
Ma-Mie Yu, Suresh K. Selvaraj, May M.Y. Liang-Chu, Sahar Aghajani, Matthew Busse, Jean Yuan, Genee Lee, Franklin V. Peale, Christiaan Klijn, Richard Bourgon, Joshua S. Kaminker, Richard M. Neve;
A resource for cell line authentication, annotation and quality control.
Nature 520:307-311(2015)

PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878
Jelle Scholtalbers, Sebastian Boegel, Thomas Bukur, Marius Byl, Sebastian Goerges, Patrick Sorn, Martin Loewer, Ugur Sahin, John C. Castle;
TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.
Genome Med. 7:118.1-118.7(2015)

PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005; PMCID=PMC5501076
Jun Li, Wei Zhao, Rehan Akbani, Wen-Bin Liu, Zhen-Lin Ju, Shi-Yun Ling, Christopher P. Vellano, Paul Roebuck, Qing-Hua Yu, A. Karina Eterovic, Lauren Averett Byers ...Show all 25 authors... , Michael A. Davies, Wan-Leng Deng, Y.N. Vashisht Gopal, Guo Chen, Erika Maria von Euw, Dennis Joseph Slamon, Dylan Conklin, John Victor Heymach, Adi F. Gazdar, John D. Minna, Jeffrey N. Myers, Yi-Ling Lu, Gordon B. Mills, Han Liang; Show fewer authors
Characterization of human cancer cell lines by reverse-phase protein arrays.
Cancer Cell 31:225-239(2017)

PubMed=29435981; DOI=10.1002/ijc.31304
Hyun Jeong Kim, Sun Kyoung Kang, Woo Sun Kwon, Tae Soo Kim, Inhye Jeong, Hei-Cheul Jeung, Michael Kragh, Ivan D. Horak, Hyun Cheol Chung, Sun Young Rha;
Forty-nine gastric cancer cell lines with integrative genomic profiling for development of c-MET inhibitor.
Int. J. Cancer 143:151-159(2018)

Cross-references
Cell line collections (Providers) JCRB; JCRB1075.1
JCRB; NIHS0334 - Discontinued
Cell line databases/resources CLO; CLO_0037141
LINCS_LDP; LCL-1534
Biological sample resources BioSample; SAMN03473261
Chemistry resources PharmacoDB; IM95m_658_2019
Encyclopedic resources Wikidata; Q54897512
Experimental variables resources EFO; EFO_0006598
Gene expression databases ArrayExpress; E-MTAB-2706
FANTOM5_SSTAR; 10796-110I4
GEO; GSM844572
GEO; GSM1374574
Polymorphism and mutation databases Cosmic; 2484953
Cosmic; 2807628
Sequence databases EGA; EGAS00001000610
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number27