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Cellosaurus HCS-2 (CVCL_2918)

[Text version]
Cell line name HCS-2
Synonyms HCS2
Accession CVCL_2918
Resource Identification Initiative To cite this cell line use: HCS-2 (RRID:CVCL_2918)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Population: Japanese.
Doubling time: ~65 hours (Note=At 17th passage) (PubMed=2979208); ~39 hours (Note=Lot 09092016) (JCRB=JCRB1203).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
HLA typing Source: PubMed=9023415
Class I
HLA-AA*24:02
HLA-BB*52:01
HLA-CC*12:02
Disease Cervical squamous cell carcinoma, not otherwise specified (NCIt: C180839)
Squamous cell carcinoma of the cervix uteri (ORDO: Orphanet_213767)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 42Y
Category Cancer cell line
STR profile Source(s): DepMap=ACH-001515; JCRB=JCRB1203; PubMed=25877200

Markers:
AmelogeninX
CSF1PO10
D2S133824
D3S135816,18
D5S81811,12
D7S82010,12
D8S117913,14
D13S31711
D16S5399,10
D18S5113,14
D19S43312,13
D21S1131.2
FGA23,24
Penta D11,13
Penta E5,21
TH016
TPOX9,11
vWA18

Run an STR similarity search on this cell line
Publications

PubMed=2979208
Morisawa T., Kuramoto H., Shimoda T., Sakamoto I., Kato Y., Hamano M.
Establishment and characterization of a new SCC antigen producing cell line (HCS-2) from a carcinoma of the uterine cervix.
Hum. Cell 1:308-314(1988)

PubMed=9023415; DOI=10.1006/cimm.1996.1062
Seki N., Hoshino T., Kikuchi M., Hayashi A., Itoh K.
HLA-A locus-restricted and tumor-specific CTLs in tumor-infiltrating lymphocytes of patients with non-small cell lung cancer.
Cell. Immunol. 175:101-110(1997)

PubMed=25877200; DOI=10.1038/nature14397
Yu M., Selvaraj S.K., Liang-Chu M.M.Y., Aghajani S., Busse M., Yuan J., Lee G., Peale F.V., Klijn C., Bourgon R., Kaminker J.S., Neve R.M.
A resource for cell line authentication, annotation and quality control.
Nature 520:307-311(2015)

Cross-references
Cell line collections (Providers) JCRB; JCRB1203
JCRB; NIHS0405 - Discontinued
Cell line databases/resources cancercelllines; CVCL_2918
Cell_Model_Passport; SIDM01815
DepMap; ACH-001515
Biological sample resources BioSample; SAMN03470913
Encyclopedic resources Wikidata; Q54881899
Entry history
Entry creation04-Apr-2012
Last entry update02-May-2024
Version number19