ID   HCS-2
AC   CVCL_2918
SY   HCS2
DR   BioSample; SAMN03470913
DR   cancercelllines; CVCL_2918
DR   Cell_Model_Passport; SIDM01815
DR   DepMap; ACH-001515
DR   JCRB; JCRB1203
DR   JCRB; NIHS0405
DR   Wikidata; Q54881899
RX   PubMed=2979208;
RX   PubMed=9023415;
RX   PubMed=25877200;
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Population: Japanese.
CC   Doubling time: ~65 hours (Note=At 17th passage) (PubMed=2979208); ~39 hours (Note=Lot 09092016) (JCRB=JCRB1203).
CC   HLA typing: A*24:02; B*52:01; C*12:02 (PubMed=9023415).
CC   Discontinued: JCRB; NIHS0405; true.
CC   Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
ST   Source(s): DepMap=ACH-001515; JCRB=JCRB1203; PubMed=25877200
ST   Amelogenin: X
ST   CSF1PO: 10
ST   D13S317: 11
ST   D16S539: 9,10
ST   D18S51: 13,14
ST   D19S433: 12,13
ST   D21S11: 31.2
ST   D2S1338: 24
ST   D3S1358: 16,18
ST   D5S818: 11,12
ST   D7S820: 10,12
ST   D8S1179: 13,14
ST   FGA: 23,24
ST   Penta D: 11,13
ST   Penta E: 5,21
ST   TH01: 6
ST   TPOX: 9,11
ST   vWA: 18
DI   NCIt; C180839; Cervical squamous cell carcinoma, not otherwise specified
DI   ORDO; Orphanet_213767; Squamous cell carcinoma of the cervix uteri
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   42Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 02-05-24; Version: 19
//
RX   PubMed=2979208;
RA   Morisawa, Takayuki
RA   Kuramoto, Hiroyuki
RA   Shimoda, Takao
RA   Sakamoto, Izumi
RA   Kato, Yoshiki
RA   Hamano, Mieko
RT   "Establishment and characterization of a new SCC antigen producing
RT   cell line (HCS-2) from a carcinoma of the uterine cervix.";
RL   Hum. Cell 1:308-314(1988).
//
RX   PubMed=9023415; DOI=10.1006/cimm.1996.1062;
RA   Seki, Naoko
RA   Hoshino, Tomoaki
RA   Kikuchi, Megumi
RA   Hayashi, Akihiro
RA   Itoh, Kyogo
RT   "HLA-A locus-restricted and tumor-specific CTLs in tumor-infiltrating
RT   lymphocytes of patients with non-small cell lung cancer.";
RL   Cell. Immunol. 175:101-110(1997).
//
RX   PubMed=25877200; DOI=10.1038/nature14397;
RA   Yu, Ma-Mie
RA   Selvaraj, Suresh K.
RA   Liang-Chu, May M.Y.
RA   Aghajani, Sahar
RA   Busse, Matthew
RA   Yuan, Jean
RA   Lee, Genee
RA   Peale, Franklin V.
RA   Klijn, Christiaan
RA   Bourgon, Richard
RA   Kaminker, Joshua S.
RA   Neve, Richard M.
RT   "A resource for cell line authentication, annotation and quality
RT   control.";
RL   Nature 520:307-311(2015).
//