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Cellosaurus HARA-B (CVCL_2915)

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Cell line name HARA-B
Synonyms HARAB
Accession CVCL_2915
Resource Identification Initiative To cite this cell line use: HARA-B (RRID:CVCL_2915)
Comments Population: Japanese.
Characteristics: Produces high level of parathyroid hormone-related peptide (PTHrP).
Omics: Transcriptomics; Microarray.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Val143Ala (c.428T>C); ClinVar=VCV000804214; Zygosity=Homozygous (from parent cell line).
Disease Lung squamous cell carcinoma (NCIt: C3493)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2914 (HARA [Human squamous cell lung carcinoma])
Children:
CVCL_A9FF (HARA-B-GFP)CVCL_4W91 (HARA-B4)
Sex of cell Male
Age at sampling 57Y
Category Cancer cell line
STR profile Source(s): CLS=300465; JCRB=JCRB1080.1

Markers:
AmelogeninX,Y
CSF1PO13
D2S133819,20
D3S135815
D5S81812
D6S104311,14
D7S82012
D8S117910,12
D12S39118,19
D13S3179
D16S53910
D18S5113
D19S43313
D21S1130
FGA20
Penta D9
Penta E11
TH017
TPOX8,9
vWA16,17

Run an STR similarity search on this cell line
Publications

PubMed=8752176
Haruo Iguchi, Shohei Tanaka, Yukiko Ozawa, Tomiko Kashiwakuma, Tatsuji Kimura, Toru Hiraga, Hidehiro Ozawa, Akira Kono;
An experimental model of bone metastasis by human lung cancer cells: the role of parathyroid hormone-related protein in bone metastasis.
Cancer Res. 56:4040-4043(1996)

PubMed=11668474; DOI=10.1002/ijc.1425
Haruo Iguchi, Etsuro Onuma, Koh Sato, Kanji Sato, Etsuro Ogata;
Involvement of parathyroid hormone-related protein in experimental cachexia induced by a human lung cancer-derived cell line established from a bone metastasis specimen.
Int. J. Cancer 94:24-27(2001)

Cross-references
Cell line collections (Providers) CLS; 300465
JCRB; JCRB1080.1
JCRB; NIHS0352.1 - Discontinued
KCB; KCB 2016077YJ
Cell line databases/resources cancercelllines; CVCL_2915
CCRID; 5301HUM-KCB16077YJ
Encyclopedic resources Wikidata; Q54881314
Gene expression databases GEO; GSM1374488
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number24