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Cellosaurus Ramos-AW (CVCL_2702)

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Cell line name Ramos-AW
Synonyms RAMOS-AW; AW-Ramos; AW-Ra #1
Accession CVCL_2702
Resource Identification Initiative To cite this cell line use: Ramos-AW (RRID:CVCL_2702)
Comments Population: Caucasian.
Virology: EBV-negative cell line infected with EBV from P3HR-1 cell line (Cellosaurus=CVCL_2676).
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Derived from site: In situ; Ascites; UBERON=UBERON_0007795.
Cell type: B-cell; CL=CL_0000236.
Sequence variations
  • Gene fusion; HGNC; HGNC:5477; IGH + HGNC; HGNC:7553; MYC; Name(s)=MYC-IGH (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Ile254Asp (c.760_761AT>GA); Zygosity=Homozygous (from parent cell line).
Disease Burkitt lymphoma (NCIt: C2912)
Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0597 (Ramos)
Children:
CVCL_C5DM (sfAWRamos)
Sex of cell Male
Age at sampling 3Y
Category Cancer cell line
STR profile Source(s): ECACC=85062003

Markers:
AmelogeninX
CSF1PO10,11
D5S8187,12
D7S82011
D13S31713,14
D16S53910,13
TH017,9.3
TPOX8,9
vWA15,16

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Publications

PubMed=181343; DOI=10.1159/000149930
George Klein, Beppino Carlo Giovanella, Anita Westman, John Sebastian Stehlin Jr., David Meday Mumford;
An EBV-genome-negative cell line established from an American Burkitt lymphoma; receptor characteristics. EBV infectibility and permanent conversion into EBV-positive sublines by in vitro infection.
Intervirology 5:319-334(1975)

PubMed=62724; DOI=10.1002/ijc.2910180513
George Klein, Jesper Zeuthen, Paul Ichiro Terasaki, Ronald James Billing, Ron Honig, Mikael Jondal, Anita Westman, Geoffrey Baverstock Clements;
Inducibility of the Epstein-Barr virus (EBV) cycle and surface marker properties of EBV-negative lymphoma lines and their in vitro EBV-converted sublines.
Int. J. Cancer 18:639-652(1976)

PubMed=3518877; DOI=10.3109/07357908609038260
Jorgen Fogh;
Human tumor lines for cancer research.
Cancer Invest. 4:157-184(1986)

PubMed=2835030; DOI=10.1016/S0385-8146(87)80025-1
Toru Takimoto, Hiroshi Sato, Hisashi Ogura, Tameo Miyazaki;
Establishment of an Epstein-Barr virus (EBV) genome-positive subline of Ramos (Ramos/NPC) following infection of Ramos with nasopharyngeal carcinoma (NPC)-derived EBV.
Auris Nasus Larynx 14:87-92(1987)

Cross-references
Cell line collections (Providers) ECACC; 85062003
Cell line databases/resources CLO; CLO_0008741
CLDB; cl4099
Anatomy/cell type resources BTO; BTO_0003077
Encyclopedic resources Wikidata; Q54949201
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number24