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Cellosaurus RAJI 'A' (CVCL_2699)

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Cell line name RAJI 'A'
Synonyms RAJI A; Raji A; RAJI'A'
Accession CVCL_2699
Resource Identification Initiative To cite this cell line use: RAJI 'A' (RRID:CVCL_2699)
Comments Population: African; Nigerian.
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Derived from site: In situ; Bone, jaw, maxilla; UBERON=UBERON_0002397.
Cell type: B-cell; CL=CL_0000236.
Sequence variations
  • Gene fusion; HGNC; HGNC:5477; IGH + HGNC; HGNC:7553; MYC; Name(s)=MYC-IGH (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg213Gln (c.638G>A); ClinVar=VCV000135359; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr234His (c.700T>C); ClinVar=VCV000376691; Zygosity=Heterozygous (from parent cell line).
Disease EBV-related Burkitt lymphoma (NCIt: C27694)
Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0511 (Raji)
Sex of cell Male
Age at sampling 11Y
Category Cancer cell line
STR profile Source(s): ECACC=85022102

Markers:
AmelogeninX,Y
CSF1PO10,12
D5S81810,13
D7S82010
D13S31713
D16S5398,11
TH016,7
TPOX8,13
vWA17,19

Run an STR similarity search on this cell line
Publications

PubMed=4122458; DOI=10.1002/ijc.2910100108
George Klein, Laszlo Dombos, Balwant Gothoskar;
Sensitivity of Epstein-Barr virus (EBV) producer and non-producer human lymphoblastoid cell lines to superinfection with EB-virus.
Int. J. Cancer 10:44-57(1972)

PubMed=4364259; DOI=10.1002/ijc.2910110210
George Klein, Laszlo Dombos;
Relationship between the sensitivity of EBV-carrying lymphoblastoid lines to superinfection and the inducibility of the resident viral genome.
Int. J. Cancer 11:327-337(1973)

Cross-references
Cell line collections (Providers) ECACC; 85022102
Cell line databases/resources CLO; CLO_0008737
CLDB; cl4093
cancercelllines; CVCL_2699
Encyclopedic resources Wikidata; Q54949145
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number24