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Cellosaurus Nthy-ori 3-1 (CVCL_2659)

[Text version]
Cell line name Nthy-ori 3-1
Synonyms Nthy ori 3.1; Nthy-ori 3.1; NTHY-ORI3.1; HTori-3.1
Accession CVCL_2659
Resource Identification Initiative To cite this cell line use: Nthy-ori 3-1 (RRID:CVCL_2659)
Comments Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=pSVori-).
Omics: Metabolomics.
Omics: Transcriptomics; Microarray.
Omics: Variations; SNP array analysis.
Derived from site: In situ; Thyroid gland; UBERON=UBERON_0002046.
Cell type: Follicular cell; CL=CL_0002258.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_4W02 (HTori-3)
Sex of cell Female
Age at sampling 35Y
Category Transformed cell line
STR profile Source(s): ECACC=90011609; PubMed=21868764; PubMed=30737244

Markers:
AmelogeninX
CSF1PO12
D3S135814,16
D5S81811
D7S8207,12
D8S117912
D13S31711
D16S53912,13
D18S5114
D21S1129,30
FGA21,22
TH017 (ECACC=90011609; PubMed=21868764)
7,9.3 (PubMed=30737244)
TPOX9
vWA16,18

Run an STR similarity search on this cell line
Publications

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662
S. Michael Rothenberg, Gayatry Mohapatra, Miguel N. Rivera, Daniel Winokur, Patricia Greninger, Mai Nitta, Peter M. Sadow, Gaya Sooriyakumar, Brian W. Brannigan, Matthew J. Ulman, Rushika M. Perera ...Show all 22 authors... , Rui Wang, Angela Tam, Xiao-Jun Ma, Mark Erlander, Dennis C. Sgroi, James W. Rocco, Mark W. Lingen, Ezra E.W. Cohen, David Neil Louis, Jeffrey Settleman, Daniel Arie Haber; Show fewer authors
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)

PubMed=21868764; DOI=10.1158/1078-0432.CCR-11-0690; PMCID=PMC3229662
Mei Zhao, Daisuke Sano, Curtis R. Pickering, Samar A. Jasser, Ying C. Henderson, Gary L. Clayman, Erich M. Sturgis, Thomas J. Ow, Reuben Lotan, Thomas E. Carey, Peter G. Sacks ...Show all 15 authors... , Jennifer Rubin Grandis, David Sidransky, Nils-Erik Heldin, Jeffrey N. Myers; Show fewer authors
Assembly and initial characterization of a panel of 85 genomically validated cell lines from diverse head and neck tumor sites.
Clin. Cancer Res. 17:7248-7264(2011)

PubMed=22087789; DOI=10.1186/1755-8166-4-26; PMCID=PMC3248874
Irena Maric, Silvia Viaggi, Paola Caria, Daniela Virginia Frau, Paolo Degan, Roberta Vanni;
Centrosomal and mitotic abnormalities in cell lines derived from papillary thyroid cancer harboring specific gene alterations.
Mol. Cytogenet. 4:26.1-26.8(2011)

PubMed=30737244; DOI=10.1158/1078-0432.CCR-18-2953; PMCID=PMC6522280
Inigo Landa, Nikita Pozdeyev, Christopher T. Korch, Laura A. Marlow, Robert Christian Smallridge, John Alton Copland 3rd, Ying C. Henderson, Stephen Y. Lai, Gary L. Clayman, Naoyoshi Onoda, Aik-Choon Tan ...Show all 16 authors... , Maria E.R. Garcia-Rendueles, Jeffrey A. Knauf, Bryan R. Haugen, James Alexander Fagin, Rebecca E. Schweppe; Show fewer authors
Comprehensive genetic characterization of human thyroid cancer cell lines: a validated panel for preclinical studies.
Clin. Cancer Res. 25:3141-3151(2019)

PubMed=36599897; DOI=10.1038/s41598-023-27461-2; PMCID=PMC9813134
Tomomi Kurashige, Mika Shimamura, Koichiro Hamada, Michiko Matsuse, Norisato Mitsutake, Yuji Nagayama;
Characterization of metabolic reprogramming by metabolomics in the oncocytic thyroid cancer cell line XTC.UC1.
Sci. Rep. 13:149.1-149.11(2023)

Cross-references
Cell line collections (Providers) ECACC; 90011609
Ubigene; YC-C089
Cell line databases/resources CLO; CLO_0008209
CLDB; cl3741
cancercelllines; CVCL_2659
Anatomy/cell type resources BTO; BTO_0004859
Encyclopedic resources Wikidata; Q54931115
Experimental variables resources EFO; EFO_0022713
Gene expression databases GEO; GSM827409
Polymorphism and mutation databases Progenetix; CVCL_2659
Entry history
Entry creation04-Apr-2012
Last entry update14-Aug-2025
Version number22