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Cellosaurus MDOK (CVCL_2587)

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Cell line name MDOK
Synonyms Madin-Darby Ovine Kidney
Accession CVCL_2587
Resource Identification Initiative To cite this cell line use: MDOK (RRID:CVCL_2587)
Comments Virology: Not susceptible to infection by SARS coronavirus 2 (SARS-CoV-2) (COVID-19) (PubMed=33389257).
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Cell type: Epithelial cell of kidney; CL=CL_0002518.
Species of origin Ovis aries (Sheep) (NCBI Taxonomy: 9940)
Sex of cell Male
Age at sampling Adult
Category Spontaneously immortalized cell line
Web pages Info; -; -; https://micro.magnet.fsu.edu/primer/techniques/fluorescence/gallery/cells/mdok/mdokcells.html
Info; Evident; -; https://evidentscientific.com/en/microscope-resource/image-gallery/confocal/epithelialindex
Publications

PubMed=13567776; DOI=10.3181/00379727-98-24111
Stewart Harvey Madin, Norman B. Darby Jr.;
Established kidney cell lines of normal adult bovine and ovine origin.
Proc. Soc. Exp. Biol. Med. 98:574-576(1958)

PubMed=14282199; DOI=10.1007/BF00320563
Walter Anthony Nelson-Rees, Alexis John Kniazeff, Norman B. Darby Jr.;
Peculiarities of ovine cells in culture.
Chromosoma 16:79-89(1965)

PubMed=5587551; DOI=10.1159/000129961
Walter Anthony Nelson-Rees, Alexis John Kniazeff, Norman B. Darby Jr.;
Debut and accumulation of centric fusion products: an index to age of certain cell lines.
Cytogenetics 6:436-450(1967)

PubMed=33389257; DOI=10.1007/s10096-020-04106-0; PMCID=PMC7778494
Nathalie Wurtz, Gwilherm Penant, Priscilla Jardot, Nathalie Duclos, Bernard La Scola;
Culture of SARS-CoV-2 in a panel of laboratory cell lines, permissivity, and differences in growth profile.
Eur. J. Clin. Microbiol. Infect. Dis. 40:477-484(2021)

Cross-references
Cell line collections (Providers) ATCC; CRL-1633
BCRJ; 0172
IZSLER; BS CL 65 - Discontinued
Cell line databases/resources CLO; CLO_0007650
CLDB; cl3427
Encyclopedic resources Wikidata; Q54904816
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number19