ID   MDOK
AC   CVCL_2587
SY   Madin-Darby Ovine Kidney
DR   CLO; CLO_0007650
DR   CLDB; cl3427
DR   ATCC; CRL-1633
DR   BCRJ; 0172
DR   IZSLER; BS CL 65
DR   Wikidata; Q54904816
RX   PubMed=5587551;
RX   PubMed=13567776;
RX   PubMed=14282199;
RX   PubMed=33389257;
WW   Info; -; -; https://micro.magnet.fsu.edu/primer/techniques/fluorescence/gallery/cells/mdok/mdokcells.html
WW   Info; Evident; -; https://evidentscientific.com/en/microscope-resource/image-gallery/confocal/epithelialindex
CC   Virology: Not susceptible to infection by SARS coronavirus 2 (SARS-CoV-2) (COVID-19) (PubMed=33389257).
CC   Discontinued: IZSLER; BS CL 65; probable.
CC   Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
CC   Cell type: Epithelial cell of kidney; CL=CL_0002518.
OX   NCBI_TaxID=9940; ! Ovis aries (Sheep)
SX   Male
AG   Adult
CA   Spontaneously immortalized cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 19
//
RX   PubMed=5587551; DOI=10.1159/000129961;
RA   Nelson-Rees W.A., Kniazeff A.J., Darby N.B. Jr.;
RT   "Debut and accumulation of centric fusion products: an index to age of
RT   certain cell lines.";
RL   Cytogenetics 6:436-450(1967).
//
RX   PubMed=13567776; DOI=10.3181/00379727-98-24111;
RA   Madin S.H., Darby N.B. Jr.;
RT   "Established kidney cell lines of normal adult bovine and ovine
RT   origin.";
RL   Proc. Soc. Exp. Biol. Med. 98:574-576(1958).
//
RX   PubMed=14282199; DOI=10.1007/BF00320563;
RA   Nelson-Rees W.A., Kniazeff A.J., Darby N.B. Jr.;
RT   "Peculiarities of ovine cells in culture.";
RL   Chromosoma 16:79-89(1965).
//
RX   PubMed=33389257; DOI=10.1007/s10096-020-04106-0; PMCID=PMC7778494;
RA   Wurtz N., Penant G., Jardot P., Duclos N., La Scola B.;
RT   "Culture of SARS-CoV-2 in a panel of laboratory cell lines,
RT   permissivity, and differences in growth profile.";
RL   Eur. J. Clin. Microbiol. Infect. Dis. 40:477-484(2021).
//