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Cellosaurus MCC14/2 (CVCL_2584)

[Text version]
Cell line name MCC14/2
Synonyms MCC14-2; MCC14/2TC; MCC14/2 TC; MCC142
Accession CVCL_2584
Resource Identification Initiative To cite this cell line use: MCC14/2 (RRID:CVCL_2584)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Omics: Genomics; Whole exome sequencing.
Derived from site: Metastatic; Iliac lymph node; UBERON=UBERON_0015878.
Sequence variations
Disease Merkel cell carcinoma (NCIt: C9231)
Cutaneous neuroendocrine carcinoma (ORDO: Orphanet_79140)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_4447 ! MCC14/1
Sex of cell Male
Age at sampling 80Y
Category Cancer cell line
STR profile Source(s): CBA=CBA-1340; DepMap=ACH-001551

Markers:
AmelogeninX
CSF1PO10 (CBA=CBA-1340)
10,11 (DepMap=ACH-001551)
D2S133819
D3S135816
D5S81813
D7S8208,10
D8S117910,14
D13S31713
D16S53913
D18S5112,15,17 (CBA=CBA-1340)
15,17 (DepMap=ACH-001551)
D19S43312,14
D21S1129,32.2
FGA21
Penta D9,12
Penta E7
TH016,9.3
TPOX8
vWA17,18

Run an STR similarity search on this cell line
Publications

PubMed=8026890; DOI=10.1002/ijc.2910580223
J. Angus F. Thomson, Joan Helen Leonard, K. McGregor, Richard A. Sturm, Peter G. Parsons;
A nonconsensus octamer-recognition sequence (TAATGARAT-motif) identifies a novel DNA binding protein in human Merkel cell carcinoma cell lines.
Int. J. Cancer 58:285-290(1994)

PubMed=7814141; DOI=10.1002/ijc.2910600115
Joan Helen Leonard, Peter Dash, Peter Holland, John Henry Kearsley, John R. Bell;
Characterisation of four Merkel cell carcinoma adherent cell lines.
Int. J. Cancer 60:100-107(1995)

PubMed=10732753; DOI=10.1054/bjoc.1999.1006; PMCID=PMC2374386
Mireille Van Gele, Mourad Kaghad, Joan Helen Leonard, Nadine Van Roy, Jean M. Naeyaert, Marie-Louise Geerts, Simon Van Belle, Veronique F. Cocquyt, Julia A. Bridge, Raf Sciot, Christiane De Wolf-Peeters ...Show all 14 authors... , Anne De Paepe, Daniel Caput, Frank Speleman; Show fewer authors
Mutation analysis of P73 and TP53 in Merkel cell carcinoma.
Br. J. Cancer 82:823-826(2000)

PubMed=11433400; DOI=10.1002/ijc.1352
Anthony L. Cook, Pamela M. Pollock, John Welch, Michael D. Walsh, Rayleen V. Bowman, Kathryn C. Baumann, Nicholas K. Hayward, Joan Helen Leonard;
CDKN2A is not the principal target of deletions on the short arm of chromosome 9 in neuroendocrine (Merkel cell) carcinoma of the skin.
Int. J. Cancer 93:361-367(2001)

PubMed=12209986; DOI=10.1002/ijc.10554
Joan Helen Leonard, Anthony L. Cook, Mireille Van Gele, Glen M. Boyle, Kelly J. Inglis, Frank Speleman, Richard A. Sturm;
Proneural and proneuroendocrine transcription factor expression in cutaneous mechanoreceptor (Merkel) cells and Merkel cell carcinoma.
Int. J. Cancer 101:103-110(2002)

Cross-references
Cell line collections (Providers) CBA; CBA-1340
ECACC; 10092303
Cell line databases/resources cancercelllines; CVCL_2584
Cell_Model_Passport; SIDM01360
DepMap; ACH-001551
Biological sample resources BioSample; SAMN07624420
Encyclopedic resources Wikidata; Q54904254
Polymorphism and mutation databases Cosmic; 912931
Cosmic; 2273914
IARC_TP53; 12478
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number24