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Cellosaurus LMH (CVCL_2580)

[Text version]
Cell line name LMH
Synonyms Leghorn Male Hepatoma cell line
Accession CVCL_2580
Resource Identification Initiative To cite this cell line use: LMH (RRID:CVCL_2580)
Comments Group: Bird cell line.
Virology: Efficient cell line for duck hepatitis B virus (DHBV) DNA synthesis following transfection with viral constructs (PubMed=2352324).
Virology: Efficiently supports the replication of avian leukosis virus subgroup J (ALV-J) (PubMed=29720272).
Transformant: ChEBI; CHEBI_34873; N-nitrosodiethylamine (Diethylnitrosamine; DEN).
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Cell type: Epithelial cell; CL=CL_0000066.
Disease Chicken hepatoma (NCIt: C134558)
Species of origin Gallus gallus (Chicken) (NCBI Taxonomy: 9031)
Breed/subspecies: White Leghorn L-M.
Hierarchy Children:
CVCL_A3FF (LMH serum-free suspension)CVCL_3465 (LMH/2A)CVCL_E0XC (Ubigene LMH MYH9 KO)
Sex of cell Male
Age at sampling 1Y4M
Category Cancer cell line
Web pages Info; Thermo Fisher; -; https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/l/cell-lines-detail-71.html
Publications

PubMed=3607775
Tokuichi Kawaguchi, Kimie Nomura, Yoko Hirayama, Tomoyuki Kitagawa;
Establishment and characterization of a chicken hepatocellular carcinoma cell line, LMH.
Cancer Res. 47:4460-4464(1987)

PubMed=2330000; DOI=10.1210/mend-4-2-201
Roberta Binder, Clinton C. MacDonald, John B.E. Burch, Catherine B. Lazier, David L. Williams;
Expression of endogenous and transfected apolipoprotein II and vitellogenin II genes in an estrogen responsive chicken liver cell line.
Mol. Endocrinol. 4:201-208(1990)

PubMed=2352324; DOI=10.1128/JVI.64.7.3249-3258.1990; PMCID=PMC249546
Lynn D. Condreay, Carol E. Aldrich, Laura Coates, William S. Mason, Tsung-Teh Wu;
Efficient duck hepatitis B virus production by an avian liver tumor cell line.
J. Virol. 64:3249-3258(1990)

PubMed=10564780; DOI=10.1016/S0304-4165(99)00159-2
Sridevi Kolluri, Kimberly K. Elbirt, Herbert Lloyd Bonkovsky;
Heme biosynthesis in a chicken hepatoma cell line (LMH): comparison with primary chick embryo liver cells (CELC).
Biochim. Biophys. Acta 1472:658-667(1999)

PubMed=19941903; DOI=10.1016/j.jviromet.2009.11.022
Axel Karger, Barbara Bettin, Matthias Lenk, Thomas Christoph Mettenleiter;
Rapid characterisation of cell cultures by matrix-assisted laser desorption/ionisation mass spectrometric typing.
J. Virol. Methods 164:116-121(2010)

PubMed=29720272; DOI=10.1186/s13567-018-0537-7; PMCID=PMC5932828
Tuo-Fan Li, Jing Xie, Lu Lv, Shu Sun, Xiao-Mei Dong, Quan Xie, Guang-Cheng Liang, Chi-Chao Xia, Hong-Xia Shao, Ai-Jian Qin, Jian-Qiang Ye;
A chicken liver cell line efficiently supports the replication of ALV-J possibly through its high level viral receptor and efficient protein expression system.
Vet. Res. 49:41.1-41.5(2018)

PubMed=34737324; DOI=10.1038/s41598-021-00779-5; PMCID=PMC8569163
Oliver Lung, Rebecca C. Candlish, Michelle Nebroski, Peter Kruckiewicz, Cody Buchanan, Mariko Moniwa;
High-throughput sequencing for species authentication and contamination detection of 63 cell lines.
Sci. Rep. 11:21657.1-21657.9(2021)

Cross-references
Cell line collections (Providers) ATCC; CRL-2117
BCRC; 60320
CCLV; CCLV-RIE 0417
CLS; 601411
JCRB; JCRB0237
NCBI_Iran; C592
Cell line databases/resources CLO; CLO_0007359
TOKU-E; 2215
Encyclopedic resources Wikidata; Q54902758
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number26