ID   LMH
AC   CVCL_2580
SY   Leghorn Male Hepatoma cell line
DR   CLO; CLO_0007359
DR   ATCC; CRL-2117
DR   BCRC; 60320
DR   CCLV; CCLV-RIE 0417
DR   CLS; 601411
DR   JCRB; JCRB0237
DR   NCBI_Iran; C592
DR   TOKU-E; 2215
DR   Wikidata; Q54902758
RX   PubMed=2330000;
RX   PubMed=2352324;
RX   PubMed=3607775;
RX   PubMed=10564780;
RX   PubMed=19941903;
RX   PubMed=29720272;
RX   PubMed=34737324;
WW   Info; Thermo Fisher; -; https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/l/cell-lines-detail-71.html
CC   Group: Bird cell line.
CC   Virology: Efficient cell line for duck hepatitis B virus (DHBV) DNA synthesis following transfection with viral constructs (PubMed=2352324).
CC   Virology: Efficiently supports the replication of avian leukosis virus subgroup J (ALV-J) (PubMed=29720272).
CC   Transformant: ChEBI; CHEBI_34873; N-nitrosodiethylamine (Diethylnitrosamine; DEN).
CC   Derived from site: In situ; Liver; UBERON=UBERON_0002107.
CC   Cell type: Epithelial cell; CL=CL_0000066.
CC   Breed/subspecies: White Leghorn L-M.
DI   NCIt; C134558; Chicken hepatoma
OX   NCBI_TaxID=9031; ! Gallus gallus (Chicken)
SX   Male
AG   1Y4M
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 26
CH   CVCL_A3FF ! LMH serum-free suspension
CH   CVCL_3465 ! LMH/2A
CH   CVCL_E0XC ! Ubigene LMH MYH9 KO
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RX   PubMed=34737324; DOI=10.1038/s41598-021-00779-5; PMCID=PMC8569163;
RA   Lung, Oliver
RA   Candlish, Rebecca C.
RA   Nebroski, Michelle
RA   Kruckiewicz, Peter
RA   Buchanan, Cody
RA   Moniwa, Mariko
RT   "High-throughput sequencing for species authentication and
RT   contamination detection of 63 cell lines.";
RL   Sci. Rep. 11:21657.1-21657.9(2021).
//
RX   PubMed=10564780; DOI=10.1016/S0304-4165(99)00159-2;
RA   Kolluri, Sridevi
RA   Elbirt, Kimberly K.
RA   Bonkovsky, Herbert Lloyd
RT   "Heme biosynthesis in a chicken hepatoma cell line (LMH): comparison
RT   with primary chick embryo liver cells (CELC).";
RL   Biochim. Biophys. Acta 1472:658-667(1999).
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RX   PubMed=19941903; DOI=10.1016/j.jviromet.2009.11.022;
RA   Karger, Axel
RA   Bettin, Barbara
RA   Lenk, Matthias
RA   Mettenleiter, Thomas Christoph
RT   "Rapid characterisation of cell cultures by matrix-assisted laser
RT   desorption/ionisation mass spectrometric typing.";
RL   J. Virol. Methods 164:116-121(2010).
//
RX   PubMed=3607775;
RA   Kawaguchi, Tokuichi
RA   Nomura, Kimie
RA   Hirayama, Yoko
RA   Kitagawa, Tomoyuki
RT   "Establishment and characterization of a chicken hepatocellular
RT   carcinoma cell line, LMH.";
RL   Cancer Res. 47:4460-4464(1987).
//
RX   PubMed=2352324; DOI=10.1128/JVI.64.7.3249-3258.1990; PMCID=PMC249546;
RA   Condreay, Lynn D.
RA   Aldrich, Carol E.
RA   Coates, Laura
RA   Mason, William S.
RA   Wu, Tsung-Teh
RT   "Efficient duck hepatitis B virus production by an avian liver tumor
RT   cell line.";
RL   J. Virol. 64:3249-3258(1990).
//
RX   PubMed=29720272; DOI=10.1186/s13567-018-0537-7; PMCID=PMC5932828;
RA   Li, Tuo-Fan
RA   Xie, Jing
RA   Lv, Lu
RA   Sun, Shu
RA   Dong, Xiao-Mei
RA   Xie, Quan
RA   Liang, Guang-Cheng
RA   Xia, Chi-Chao
RA   Shao, Hong-Xia
RA   Qin, Ai-Jian
RA   Ye, Jian-Qiang
RT   "A chicken liver cell line efficiently supports the replication of
RT   ALV-J possibly through its high level viral receptor and efficient
RT   protein expression system.";
RL   Vet. Res. 49:41.1-41.5(2018).
//
RX   PubMed=2330000; DOI=10.1210/mend-4-2-201;
RA   Binder, Roberta
RA   MacDonald, Clinton C.
RA   Burch, John B.E.
RA   Lazier, Catherine B.
RA   Williams, David L.
RT   "Expression of endogenous and transfected apolipoprotein II and
RT   vitellogenin II genes in an estrogen responsive chicken liver cell
RT   line.";
RL   Mol. Endocrinol. 4:201-208(1990).
//