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Cellosaurus AT2BR LCL (CVCL_2564)

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Cell line name AT2BR LCL
Synonyms Ataxia Telangiectasia 2 BRighton LCL; LB58; 58
Accession CVCL_2564
Resource Identification Initiative To cite this cell line use: AT2BR LCL (RRID:CVCL_2564)
Comments Population: Caucasian; Irish.
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Mutation; HGNC; HGNC:795; ATM; Simple; p.Arg2547_Ser2549del (c.7638_7646delTAGAATTTC) (7636del9); ClinVar=VCV000003019; Zygosity=Homozygous (from autologous cell line AT2BR).
Disease Ataxia telangiectasia syndrome (NCIt: C2887)
Ataxia telangiectasia (ORDO: Orphanet_100)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_WY25 ! AT2BR
Sex of cell Female
Age at sampling 13Y
Category Transformed cell line
Publications

PubMed=7836839; DOI=10.1080/09553009414551951
Jane Cole, Colin Francis Arlett;
Cloning efficiency and spontaneous mutant frequency in circulating T-lymphocytes in ataxia-telangiectasia patients.
Int. J. Radiat. Biol. 66:S123-S131(1994)

Cross-references
Cell line collections (Providers) ECACC; 98062325
Encyclopedic resources Wikidata; Q54902072
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number15