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Cellosaurus Karpas-25 (CVCL_2540)

[Text version]
Cell line name Karpas-25
Synonyms KARPAS-25; Karpas 25; KARPAS 25; Karpas25
Accession CVCL_2540
Resource Identification Initiative To cite this cell line use: Karpas-25 (RRID:CVCL_2540)
Comments Doubling time: ~30 hours (ECACC=06072601; Ximbio=152420).
Omics: Transcriptomics; RNAseq.
Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
Cell type: Plasma cell; CL=CL_0000786.
Disease Plasma cell myeloma (NCIt: C3242)
Multiple myeloma (ORDO: Orphanet_29073)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 27Y
Category Cancer cell line
Web pages Info; Keats Lab; -; https://www.keatslab.org/myeloma-cell-lines
Provider; Cambridge Enterprise; -; https://www.enterprise.cam.ac.uk/reagents/karpas-25-human-myeloma-cell-line/
Publications

PubMed=10936422; DOI=10.1016/S0145-2126(99)00195-2
Hans Gunther Drexler, Yoshinobu Matsuo;
Malignant hematopoietic cell lines: in vitro models for the study of multiple myeloma and plasma cell leukemia.
Leuk. Res. 24:681-703(2000)

PubMed=15621787; DOI=10.1080/10428190400002244
Abraham Karpas, Lana Harder, Barbara H. Czepulkowski, David Bloxham, Rani Saward, Alla Dremucheva, Reiner Siebert;
Studies of four new human myeloma cell lines.
Leuk. Lymphoma 46:101-112(2005)

CLPUB00604
Sharon Chow;
Targeted capture and sequencing of immunoglobulin rearrangements in multiple myeloma to enable detection of minimal residual disease.
Thesis MSc (2017); University of Toronto; Toronto; Canada

PubMed=32123307; DOI=10.1038/s41375-020-0785-1; PMCID=PMC7483300
Vishesh Sarin, Katharine Yu, Ian D. Ferguson, Olivia Gugliemini, Matthew A. Nix, Byron Hann, Marina Sirota, Arun P. Wiita;
Evaluating the efficacy of multiple myeloma cell lines as models for patient tumors via transcriptomic correlation analysis.
Leukemia 34:2754-2765(2020)

Cross-references
Cell line collections (Providers) ECACC; 06072601
Ximbio; 152420
Encyclopedic resources Wikidata; Q54899494
Entry history
Entry creation04-Apr-2012
Last entry update14-Aug-2025
Version number18