ID   Karpas-25
AC   CVCL_2540
SY   KARPAS-25; Karpas 25; KARPAS 25; Karpas25
DR   ECACC; 06072601
DR   Wikidata; Q54899494
DR   Ximbio; 152420
RX   CelloPub=CLPUB00604;
RX   PubMed=10936422;
RX   PubMed=15621787;
RX   PubMed=32123307;
WW   Info; Keats Lab; -; https://www.keatslab.org/myeloma-cell-lines
WW   Provider; Cambridge Enterprise; -; https://www.enterprise.cam.ac.uk/reagents/karpas-25-human-myeloma-cell-line/
CC   Doubling time: ~30 hours (ECACC=06072601; Ximbio=152420).
CC   Omics: Transcriptomics; RNAseq.
CC   Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
CC   Cell type: Plasma cell; CL=CL_0000786.
DI   NCIt; C3242; Plasma cell myeloma
DI   ORDO; Orphanet_29073; Multiple myeloma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   27Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 14-08-25; Version: 18
//
RX   PubMed=10936422; DOI=10.1016/S0145-2126(99)00195-2;
RA   Drexler, Hans Gunther
RA   Matsuo, Yoshinobu
RT   "Malignant hematopoietic cell lines: in vitro models for the study of
RT   multiple myeloma and plasma cell leukemia.";
RL   Leuk. Res. 24:681-703(2000).
//
RX   CelloPub=CLPUB00604;
RA   Chow, Sharon
RT   "Targeted capture and sequencing of immunoglobulin rearrangements
RT   in multiple myeloma to enable detection of minimal residual disease.";
RL   Thesis MSc (2017); University of Toronto; Toronto; Canada.
//
RX   PubMed=32123307; DOI=10.1038/s41375-020-0785-1; PMCID=PMC7483300;
RA   Sarin, Vishesh
RA   Yu, Katharine
RA   Ferguson, Ian D.
RA   Gugliemini, Olivia
RA   Nix, Matthew A.
RA   Hann, Byron
RA   Sirota, Marina
RA   Wiita, Arun P.
RT   "Evaluating the efficacy of multiple myeloma cell lines as models for
RT   patient tumors via transcriptomic correlation analysis.";
RL   Leukemia 34:2754-2765(2020).
//
RX   PubMed=15621787; DOI=10.1080/10428190400002244;
RA   Karpas, Abraham
RA   Harder, Lana
RA   Czepulkowski, Barbara H.
RA   Bloxham, David
RA   Saward, Rani
RA   Dremucheva, Alla
RA   Siebert, Reiner
RT   "Studies of four new human myeloma cell lines.";
RL   Leuk. Lymphoma 46:101-112(2005).
//