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Cellosaurus JU77 (CVCL_2536)

[Text version]
Cell line name JU77
Accession CVCL_2536
Resource Identification Initiative To cite this cell line use: JU77 (RRID:CVCL_2536)
Comments Doubling time: 25 hours (PubMed=1703129).
Transformant: ChEBI; CHEBI_46666; Crocidolite asbestos.
Omics: Proteomics; Subcellular; Exosome.
Omics: Proteomics; Subcellular; Secretome.
Omics: Variations; SNP array analysis.
Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
Disease Pleural epithelioid mesothelioma (NCIt: C45662)
Pleural mesothelioma (ORDO: Orphanet_50251)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 62Y
Category Cancer cell line
STR profile Source(s): CBA=CBA-0140

Markers:
AmelogeninX,Y
CSF1PO10
D2S133817,26
D3S135814,18
D5S81811,13
D7S82010,11
D8S117913,14
D13S31711
D16S53912
D18S5116
D19S43313,14
D21S1130,32.2
FGA19,22
TH019.3
TPOX8,11
vWA15,18

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Publications

PubMed=1703129; DOI=10.1002/ijc.2910470219
Manning L.S., Whitaker D., Murch A.R., Garlepp M.J., Davis M.R., Musk A.W., Robinson B.W.S.
Establishment and characterization of five human malignant mesothelioma cell lines derived from pleural effusions.
Int. J. Cancer 47:285-290(1991)

PubMed=21642991; DOI=10.1038/ng.855; PMCID=PMC4643098
Bott M.J., Brevet M., Taylor B.S., Shimizu S., Ito T., Wang L., Creaney J., Lake R.A., Zakowski M.F., Reva B., Sander C., Delsite R., Powell S.N., Zhou Q., Shen R.-L., Olshen A.B., Rusch V.W., Ladanyi M.
The nuclear deubiquitinase BAP1 is commonly inactivated by somatic mutations and 3p21.1 losses in malignant pleural mesothelioma.
Nat. Genet. 43:668-672(2011)

PubMed=27605433; DOI=10.1038/srep32643; PMCID=PMC5015102
Greening D.W., Ji H., Chen M.-S., Robinson B.W.S., Dick I.M., Creaney J., Simpson R.J.
Secreted primary human malignant mesothelioma exosome signature reflects oncogenic cargo.
Sci. Rep. 6:32643-32643(2016)

PubMed=28387650; DOI=10.21873/cgp.20023; PMCID=PMC5369310
Creaney J., Dick I.M., Leon J.S., Robinson B.W.S.
A proteomic analysis of the malignant mesothelioma secretome using iTRAQ.
Cancer Genomics Proteomics 14:103-117(2017)

Cross-references
Cell line collections (Providers) CBA; CBA-0140
ECACC; 10092309
Cell line databases/resources cancercelllines; CVCL_2536
Biological sample resources BioSample; SAMN07624409
BioSamples; SAMEA100897
Encyclopedic resources Wikidata; Q54899115
Gene expression databases GEO; GSM726272
Polymorphism and mutation databases Cosmic; 1522780
Cosmic; 1963329
Progenetix; CVCL_2536
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number22