ID   JU77
AC   CVCL_2536
DR   BioSample; SAMN07624409
DR   BioSamples; SAMEA100897
DR   cancercelllines; CVCL_2536
DR   CBA; CBA-0140
DR   Cosmic; 1522780
DR   Cosmic; 1963329
DR   ECACC; 10092309
DR   GEO; GSM726272
DR   Progenetix; CVCL_2536
DR   Wikidata; Q54899115
RX   PubMed=1703129;
RX   PubMed=21642991;
RX   PubMed=27605433;
RX   PubMed=28387650;
CC   Doubling time: 25 hours (PubMed=1703129).
CC   Transformant: ChEBI; CHEBI_46666; Crocidolite asbestos.
CC   Omics: Proteomics; Subcellular; Exosome.
CC   Omics: Proteomics; Subcellular; Secretome.
CC   Omics: Variations; SNP array analysis.
CC   Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
ST   Source(s): CBA=CBA-0140
ST   Amelogenin: X,Y
ST   CSF1PO: 10
ST   D13S317: 11
ST   D16S539: 12
ST   D18S51: 16
ST   D19S433: 13,14
ST   D21S11: 30,32.2
ST   D2S1338: 17,26
ST   D3S1358: 14,18
ST   D5S818: 11,13
ST   D7S820: 10,11
ST   D8S1179: 13,14
ST   FGA: 19,22
ST   TH01: 9.3
ST   TPOX: 8,11
ST   vWA: 15,18
DI   NCIt; C45662; Pleural epithelioid mesothelioma
DI   ORDO; Orphanet_50251; Pleural mesothelioma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   62Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 22
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RX   PubMed=28387650; DOI=10.21873/cgp.20023; PMCID=PMC5369310;
RA   Creaney, Jenette
RA   Dick, Ian M.
RA   Leon, Justine S.
RA   Robinson, Bruce William Stanley
RT   "A proteomic analysis of the malignant mesothelioma secretome using
RT   iTRAQ.";
RL   Cancer Genomics Proteomics 14:103-117(2017).
//
RX   PubMed=1703129; DOI=10.1002/ijc.2910470219;
RA   Manning, Linda S.
RA   Whitaker, Darrel
RA   Murch, Ashleigh R.
RA   Garlepp, Michael J.
RA   Davis, Mark R.
RA   Musk, Arthur William
RA   Robinson, Bruce William Stanley
RT   "Establishment and characterization of five human malignant
RT   mesothelioma cell lines derived from pleural effusions.";
RL   Int. J. Cancer 47:285-290(1991).
//
RX   PubMed=21642991; DOI=10.1038/ng.855; PMCID=PMC4643098;
RA   Bott, Matthew J.
RA   Brevet, Marie
RA   Taylor, Barry Stephen
RA   Shimizu, Shigeki
RA   Ito, Tatsuo
RA   Wang, Lu
RA   Creaney, Jenette
RA   Lake, Richard A.
RA   Zakowski, Maureen F.
RA   Reva, Boris A.
RA   Sander, Chris
RA   Delsite, Robert
RA   Powell, Simon N.
RA   Zhou, Qin
RA   Shen, Rong-Lai
RA   Olshen, Adam B.
RA   Rusch, Valerie W.
RA   Ladanyi, Marc
RT   "The nuclear deubiquitinase BAP1 is commonly inactivated by somatic
RT   mutations and 3p21.1 losses in malignant pleural mesothelioma.";
RL   Nat. Genet. 43:668-672(2011).
//
RX   PubMed=27605433; DOI=10.1038/srep32643; PMCID=PMC5015102;
RA   Greening, David W.
RA   Ji, Hong
RA   Chen, Mao-Shan
RA   Robinson, Bruce William Stanley
RA   Dick, Ian M.
RA   Creaney, Jenette
RA   Simpson, Richard J.
RT   "Secreted primary human malignant mesothelioma exosome signature
RT   reflects oncogenic cargo.";
RL   Sci. Rep. 6:32643-32643(2016).
//