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Cellosaurus HT29/219 (CVCL_2521)

[Text version]
Cell line name HT29/219
Synonyms HT-29/219; HT29219
Accession CVCL_2521
Secondary accession CVCL_6835
Resource Identification Initiative To cite this cell line use: HT29/219 (RRID:CVCL_2521)
Comments Part of: MD Anderson Cell Lines Project.
Population: Caucasian.
Omics: Protein expression by reverse-phase protein arrays.
Derived from site: In situ; Colon; UBERON=UBERON_0001155.
Sequence variations
  • Mutation; HGNC; 583; APC; Simple; p.Glu853Ter (c.2557G>T); ClinVar=VCV001071632; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 583; APC; Simple; p.Thr1556Asnfs*3 (c.4666dupA) (c.4666_4667insA); ClinVar=VCV000428112; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 8975; PIK3CA; Simple; p.Pro449Thr (c.1345C>A); ClinVar=VCV001333250; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 6770; SMAD4; Simple; p.Gln311Ter (c.931C>T); ClinVar=VCV000230663; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Homozygous (from parent cell line).
Disease Colon adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0320 (HT-29)
Sex of cell Female
Age at sampling 44Y
Category Cancer cell line
STR profile Source(s): ECACC; PubMed=17254797

Markers:
AmelogeninX
CSF1PO11 (PubMed=17254797)
11,12 (ECACC)
D3S135815,17
D5S81811,12
D7S82010
D8S117910
D13S31711 (PubMed=17254797)
11,12 (ECACC)
D16S53911,12
D18S5113
D21S1128,30
FGA19,21
TH016,9
TPOX8,9
vWA17,19

Run an STR similarity search on this cell line
Web pages https://tcpaportal.org/mclp/
Publications

PubMed=17254797; DOI=10.1016/j.biologicals.2006.10.001
Azari S., Ahmadi N., Tehrani M.J., Shokri F.
Profiling and authentication of human cell lines using short tandem repeat (STR) loci: report from the National Cell Bank of Iran.
Biologicals 35:195-202(2007)

PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005
Li J., Zhao W., Akbani R., Liu W.-B., Ju Z.-L., Ling S.-Y., Vellano C.P., Roebuck P., Yu Q.-H., Eterovic A.K., Byers L.A., Davies M.A., Deng W.-L., Gopal Y.N.V., Chen G., von Euw E.M., Slamon D.J., Conklin D., Heymach J.V., Gazdar A.F., Minna J.D., Myers J.N., Lu Y.-L., Mills G.B., Liang H.
Characterization of human cancer cell lines by reverse-phase protein arrays.
Cancer Cell 31:225-239(2017)

Cross-references
Cell line collections (Providers) ECACC; 85061109
NCBI_Iran; C154
Cell line databases/resources CLO; CLO_0004285
CLDB; cl1758
cancercelllines; CVCL_2521
Anatomy/cell type resources BTO; BTO:0002838
Encyclopedic resources Wikidata; Q54896595
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number25