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Cellosaurus AtT-20 (CVCL_2300)

[Text version]
Cell line name AtT-20
Synonyms AtT 20; ATT-20; AtT20
Accession CVCL_2300
Resource Identification Initiative To cite this cell line use: AtT-20 (RRID:CVCL_2300)
Comments Doubling time: ~3 days (Note=Lot 11152004) (JCRB=JCRB9098).
Omics: SNP array analysis.
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Pituitary gland; UBERON=UBERON_0000007.
Disease Mouse pituitary gland neoplasms (NCIt: C24037)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: LAF1.
Hierarchy Children:
CVCL_XA98 (AtT-20-FlpIn)CVCL_4W08 (AtT-20/D16v)CVCL_C6XD (AtT-20/HNP)
CVCL_1G40 (AtT-20ins)CVCL_1G39 (AtT-20ins4b/1)
Category Cancer cell line
Web pages https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/a/cell-lines-detail-156.html

PubMed=13874682; DOI=10.1073/pnas.48.7.1184
Buonassisi V., Sato G.H., Cohen A.I.
Hormone-producing cultures of adrenal and pituitary tumor origin.
Proc. Natl. Acad. Sci. U.S.A. 48:1184-1190(1962)

Stulberg C.S., Coriell L.L., Kniazeff A.J., Shannon J.E.
The animal cell culture collection.
In Vitro 5:1-16(1970)

PubMed=6317196; DOI=10.1016/0092-8674(83)90187-3
Moore H.-P.H., Walker M.D., Lee F., Kelly R.B.
Expressing a human proinsulin cDNA in a mouse ACTH-secreting cell Intracellular storage, proteolytic processing, and secretion on stimulation.
Cell 35:531-538(1983)

PubMed=2177466; DOI=10.1007/BF02624442
Vedder H.
Serum-free culture of AtT 20 pituitary cells: a system for neuroendocrine studies under defined conditions.
In Vitro Cell. Dev. Biol. 26:1068-1072(1990)

PubMed=8383976; DOI=10.1677/jme.0.0100025
Farrell W.E., Stewart M.F., Clark A.J.L., Crosby S.R., Davis J.R.E., White A.
Glucocorticoid inhibition of ACTH peptides: small cell lung cancer cell lines are more resistant than pituitary corticotroph adenoma cells.
J. Mol. Endocrinol. 10:25-32(1993)

PubMed=15541569; DOI=10.1016/j.mce.2004.07.018
Ooi G.T., Tawadros N., Escalona R.M.
Pituitary cell lines and their endocrine applications.
Mol. Cell. Endocrinol. 228:1-21(2004)

PubMed=21214938; DOI=10.1186/1471-2164-12-14
Atwood B.K., Lopez J., Wager-Miller J., Mackie K., Straiker A.
Expression of G protein-coupled receptors and related proteins in HEK293, AtT20, BV2, and N18 cell lines as revealed by microarray analysis.
BMC Genomics 12:14.1-14.14(2011)

PubMed=25277546; DOI=10.1186/1471-2164-15-847
Didion J.P., Buus R.J., Naghashfar Z., Threadgill D.W., Morse H.C. III, Pardo-Manuel de Villena F.
SNP array profiling of mouse cell lines identifies their strains of origin and reveals cross-contamination and widespread aneuploidy.
BMC Genomics 15:847.1-847.11(2014)

Cell line collections (Providers) ATCC; CCL-89
BCRC; 60244
CLS; 305161
ECACC; 87021902
KCB; KCB 93012YJ
Cell line databases/resources CLO; CLO_0001765
CLO; CLO_0001766
CLDB; cl296
CCRID; 1101MOU-PUMC000061
Lonza; 228
TOKU-E; 566
TOKU-E; 4284
Anatomy/cell type resources BTO; BTO:0001077
Chemistry resources ChEMBL-Cells; CHEMBL3307387
ChEMBL-Targets; CHEMBL614523
PubChem_Cell_line; CVCL_2300
Encyclopedic resources Wikidata; Q54751294
Gene expression databases GEO; GSM635464
GEO; GSM635465
GEO; GSM635466
GEO; GSM635467
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number25