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Cellosaurus 1BR.3.N (CVCL_2282)

[Text version]
Cell line name 1BR.3.N
Synonyms 1BR3.N; 1BR.3N; 1BR.3NEO; 1BR.3neo; 1BR3neo; 1BRneo
Accession CVCL_2282
Resource Identification Initiative To cite this cell line use: 1BR.3.N (RRID:CVCL_2282)
Comments Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=pSV3-neo).
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Fibroblast of skin; CL=CL_0002620.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2279 (1BR3)
Sex of cell Male
Age at sampling 23Y
Category Transformed cell line
STR profile Source(s): ECACC=90020508; PubMed=11416159

Markers:
AmelogeninX,Y
CSF1PO9,13
D5S81812
D7S8208,10
D8S117912,14
D13S3179,12
D16S53912,14
D21S1130
FGA21,22
TH019.3
TPOX11
vWA14,15

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Publications

PubMed=2903889; DOI=10.1080/09553008814552321
Colin Francis Arlett, Michael H.L. Green, Anne Priestley, Susan A. Harcourt, Lynne V. Mayne;
Comparative human cellular radiosensitivity: I. The effect of SV40 transformation and immortalisation on the gamma-irradiation survival of skin derived fibroblasts from normal individuals and from ataxia-telangiectasia patients and heterozygotes.
Int. J. Radiat. Biol. 54:911-928(1988)

PubMed=1549511; DOI=10.1093/nar/20.5.991; PMCID=PMC312081
Christopher J. Jones, James Edward Cleaver, Richard Dean Wood;
Repair of damaged DNA by extracts from a xeroderma pigmentosum complementation group A revertant and expression of a protein absent in its parental cell line.
Nucleic Acids Res. 20:991-995(1992)

PubMed=7519740; DOI=10.1016/0165-7992(94)90014-0
Christopher J. Jones, R. Stephen Lloyd, Richard Dean Wood;
Analysis of cells harboring a putative DNA repair gene reveals a lack of evidence for a second independent xeroderma pigmentosum group A correcting gene.
Mutat. Res. 324:159-164(1994)

PubMed=11416159; DOI=10.1073/pnas.121616198; PMCID=PMC35459
John R.W. Masters, Jim A. Thomson, Bernadette Daly-Burns, Yvonne A. Reid, Wilhelm Gerhard Dirks, Phil Packer, Lorraine H. Toji, Tadao Ohno, Hideyuki Tanabe, Colin Francis Arlett, Lloyd R. Kelland ...Show all 16 authors... , Maureen Harrison, Arvind K. Virmani, Timothy H. Ward, Karen L. Ayres, Paul G. Debenham; Show fewer authors
Short tandem repeat profiling provides an international reference standard for human cell lines.
Proc. Natl. Acad. Sci. U.S.A. 98:8012-8017(2001)

PubMed=12604777; DOI=10.1073/pnas.0437964100; PMCID=PMC151363
Yan Dai, Boris Kysela, Les A. Hanakahi, Kostas Manolis, Enriqueta Riballo, Markus Stumm, Terry Odell Harville, Stephen Craig West, Marjorie Ann Oettinger, Penelope Ann Jeggo;
Nonhomologous end joining and V(D)J recombination require an additional factor.
Proc. Natl. Acad. Sci. U.S.A. 100:2462-2467(2003)

PubMed=16714754; DOI=10.1259/bjr/83726649
Colin Francis Arlett, Piers N. Plowman, Paul Bryan Rogers, Christopher N. Parris, Fatemeh Abbaszadeh, Michael H.L. Green, Trevor J. McMillan, Cyd Bush, Nicolas Foray, Alan R. Lehmann;
Clinical and cellular ionizing radiation sensitivity in a patient with xeroderma pigmentosum.
Br. J. Radiol. 79:510-517(2006)

Cross-references
Cell line collections (Providers) ECACC; 90020508
Cell line databases/resources CLO; CLO_0001156
CLDB; cl30
Encyclopedic resources Wikidata; Q54582781
Entry history
Entry creation04-Apr-2012
Last entry update14-Aug-2025
Version number17