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Cellosaurus 1BR.3.G (CVCL_2280)

[Text version]
Cell line name 1BR.3.G
Synonyms 1BR.3-G; 1BR3.G; 1BR.3GPT; 1BR.3gpt
Accession CVCL_2280
Resource Identification Initiative To cite this cell line use: 1BR.3.G (RRID:CVCL_2280)
Comments Genetic integration: Method=Transfection; Gene=UniProtKB; P0A9M5; Escherichia coli gpt.
Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=pSV3-gpt).
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Fibroblast of skin; CL=CL_0002620.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2279 (1BR3)
Children:
CVCL_2281 (1BR.3.GN)
Sex of cell Male
Age at sampling 23Y
Category Transformed cell line
STR profile Source(s): PubMed=11416159

Markers:
AmelogeninX,Y
D8S117912,14
D18S5112,14
D21S1130
FGA21,22
TH019.3
vWA14,15

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Publications

PubMed=3002824; DOI=10.1016/0014-4827(86)90356-3
Lynne V. Mayne, Anne Priestley, Michael R. James, Julian F. Burke;
Efficient immortalization and morphological transformation of human fibroblasts by transfection with SV40 DNA linked to a dominant marker.
Exp. Cell Res. 162:530-538(1986)

PubMed=2903889; DOI=10.1080/09553008814552321
Colin Francis Arlett, Michael H.L. Green, Anne Priestley, Susan A. Harcourt, Lynne V. Mayne;
Comparative human cellular radiosensitivity: I. The effect of SV40 transformation and immortalisation on the gamma-irradiation survival of skin derived fibroblasts from normal individuals and from ataxia-telangiectasia patients and heterozygotes.
Int. J. Radiat. Biol. 54:911-928(1988)

PubMed=11416159; DOI=10.1073/pnas.121616198; PMCID=PMC35459
John R.W. Masters, Jim A. Thomson, Bernadette Daly-Burns, Yvonne A. Reid, Wilhelm Gerhard Dirks, Phil Packer, Lorraine H. Toji, Tadao Ohno, Hideyuki Tanabe, Colin Francis Arlett, Lloyd R. Kelland ...Show all 16 authors... , Maureen Harrison, Arvind K. Virmani, Timothy H. Ward, Karen L. Ayres, Paul G. Debenham; Show fewer authors
Short tandem repeat profiling provides an international reference standard for human cell lines.
Proc. Natl. Acad. Sci. U.S.A. 98:8012-8017(2001)

PubMed=16714754; DOI=10.1259/bjr/83726649
Colin Francis Arlett, Piers N. Plowman, Paul Bryan Rogers, Christopher N. Parris, Fatemeh Abbaszadeh, Michael H.L. Green, Trevor J. McMillan, Cyd Bush, Nicolas Foray, Alan R. Lehmann;
Clinical and cellular ionizing radiation sensitivity in a patient with xeroderma pigmentosum.
Br. J. Radiol. 79:510-517(2006)

Cross-references
Cell line collections (Providers) ECACC; 90020507
Cell line databases/resources CLO; CLO_0001154
CLDB; cl28
Anatomy/cell type resources BTO; BTO_0004971
Encyclopedic resources Wikidata; Q54582777
Entry history
Entry creation04-Apr-2012
Last entry update14-Aug-2025
Version number20