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Cellosaurus 1-5c-4 (CVCL_2260)

[Text version]
Cell line name 1-5c-4
Synonyms Clone 1-5c-4; Clone 1-5c-4 WKD of Chang Conjunctiva; Wong-Kilbourne derivative of Chang conjunctiva; ChWK
Accession CVCL_2260
Resource Identification Initiative To cite this cell line use: 1-5c-4 (RRID:CVCL_2260)
Comments Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=566722; PubMed=20143388). Originally thought to originate from the conjunctiva of a child.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00298.
Population: African American.
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Omics: Transcriptome analysis by microarray.
Derived from sampling site: Uterus; cervix.
Disease Human papillomavirus-related endocervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0030 (HeLa)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
STR profile Source(s): ATCC; KCLB

Markers:
AmelogeninX
CSF1PO9,10
D3S135815,18
D5S81811,12
D7S8208,12
D13S31712,13.3
D16S5399,10
FGA18,21
TH017
TPOX8,12
vWA16,18

Run an STR similarity search on this cell line
Web pages https://iclac.org/wp-content/uploads/Cross-Contaminations_v12_distribution.xlsx
Publications

DOI=10.1007/BF02618370
Stulberg C.S., Coriell L.L., Kniazeff A.J., Shannon J.E.
The animal cell culture collection.
In Vitro 5:1-16(1970)

PubMed=566722; DOI=10.1007/BF02616110
Lavappa K.S.
Survey of ATCC stocks of human cell lines for HeLa contamination.
In Vitro 14:469-475(1978)

PubMed=19630270; DOI=10.3727/105221609788681231
Tong L., Diebold Y., Calonge M., Gao J.-P., Stern M.E., Beuerman R.W.
Comparison of gene expression profiles of conjunctival cell lines with primary cultured conjunctival epithelial cells and human conjunctival tissue.
Gene Expr. 14:265-278(2009)

PubMed=20143388; DOI=10.1002/ijc.25242
Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I.
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

Cross-references
Cell line collections ATCC; CCL-20.2
ECACC; 88021103
IZSLER; BS CL 93
KCLB; 10020.2
Cell line databases/resources CLO; CLO_0002500
CLO; CLO_0002501
CLDB; cl793
CLDB; cl794
CLDB; cl795
Biological sample resources BioSample; SAMN03151673
Encyclopedic resources Wikidata; Q54399838
Entry history
Entry creation04-Apr-2012
Last entry update21-Mar-2023
Version number23