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Cellosaurus 1-5c-4 (CVCL_2260)

[Text version]
Cell line name 1-5c-4
Synonyms Clone 1-5c-4; Clone 1-5c-4 WKD of Chang Conjunctiva; Wong-Kilbourne derivative of Chang conjunctiva; ChWK
Accession CVCL_2260
Resource Identification Initiative To cite this cell line use: 1-5c-4 (RRID:CVCL_2260)
Comments Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=566722; PubMed=20143388). Originally thought to originate from the conjunctiva of a child.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00298.
Population: African American.
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related endocervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0030 (HeLa)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
STR profile Source(s): ATCC=CCL-20.2; KCLB=10020.2

Markers:
AmelogeninX
CSF1PO9,10
D2S133817
D3S135815,18
D5S81811,12
D7S8208,12
D8S117912
D13S31712,13.3
D16S5399,10
D18S5116
D19S43313,14
D21S1127,28
FGA18,21
Penta D8,15
Penta E7,17
TH017
TPOX8,12
vWA16,18

Run an STR similarity search on this cell line
Web pages Info; ICLAC; -; https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
Publications

DOI=10.1007/BF02618370
Stulberg C.S., Coriell L.L., Kniazeff A.J., Shannon J.E.
The animal cell culture collection.
In Vitro 5:1-16(1970)

PubMed=566722; DOI=10.1007/BF02616110
Lavappa K.S.
Survey of ATCC stocks of human cell lines for HeLa contamination.
In Vitro 14:469-475(1978)

PubMed=19630270; DOI=10.3727/105221609788681231; PMCID=PMC6042047
Tong L., Diebold Y., Calonge M., Gao J.-P., Stern M.E., Beuerman R.W.
Comparison of gene expression profiles of conjunctival cell lines with primary cultured conjunctival epithelial cells and human conjunctival tissue.
Gene Expr. 14:265-278(2009)

PubMed=20143388; DOI=10.1002/ijc.25242
Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I.
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

Cross-references
Cell line collections (Providers) ATCC; CCL-20.2
ECACC; 88021103
IZSLER; BS CL 93
KCLB; 10020.2
Cell line databases/resources CLO; CLO_0002500
CLO; CLO_0002501
CLDB; cl793
CLDB; cl794
CLDB; cl795
Biological sample resources BioSample; SAMN03151673
Encyclopedic resources Wikidata; Q54399838
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number27