ID   1-5c-4
AC   CVCL_2260
SY   Clone 1-5c-4; Clone 1-5c-4 WKD of Chang Conjunctiva; Wong-Kilbourne derivative of Chang conjunctiva; ChWK
DR   CLO; CLO_0002500
DR   CLO; CLO_0002501
DR   CLDB; cl793
DR   CLDB; cl794
DR   CLDB; cl795
DR   ATCC; CCL-20.2
DR   BioSample; SAMN03151673
DR   ECACC; 88021103
DR   IZSLER; BS CL 93
DR   KCLB; 10020.2
DR   Wikidata; Q54399838
RX   DOI=10.1007/BF02618370;
RX   PubMed=566722;
RX   PubMed=19630270;
RX   PubMed=20143388;
WW   https://iclac.org/wp-content/uploads/Cross-Contaminations_v12_distribution.xlsx
CC   Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=566722; PubMed=20143388). Originally thought to originate from the conjunctiva of a child.
CC   Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00298.
CC   Population: African American.
CC   Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
CC   Omics: Transcriptome analysis by microarray.
CC   Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
ST   Source(s): ATCC; KCLB
ST   Amelogenin: X
ST   CSF1PO: 9,10
ST   D13S317: 12,13.3
ST   D16S539: 9,10
ST   D3S1358: 15,18
ST   D5S818: 11,12
ST   D7S820: 8,12
ST   FGA: 18,21
ST   TH01: 7
ST   TPOX: 8,12
ST   vWA: 16,18
DI   NCIt; C27677; Human papillomavirus-related cervical adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0030 ! HeLa
SX   Female
AG   30Y6M
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 05-10-23; Version: 25
//
RX   DOI=10.1007/BF02618370;
RA   Stulberg C.S., Coriell L.L., Kniazeff A.J., Shannon J.E.;
RT   "The animal cell culture collection.";
RL   In Vitro 5:1-16(1970).
//
RX   PubMed=566722; DOI=10.1007/BF02616110;
RA   Lavappa K.S.;
RT   "Survey of ATCC stocks of human cell lines for HeLa contamination.";
RL   In Vitro 14:469-475(1978).
//
RX   PubMed=19630270; DOI=10.3727/105221609788681231;
RA   Tong L., Diebold Y., Calonge M., Gao J.-P., Stern M.E., Beuerman R.W.;
RT   "Comparison of gene expression profiles of conjunctival cell lines
RT   with primary cultured conjunctival epithelial cells and human
RT   conjunctival tissue.";
RL   Gene Expr. 14:265-278(2009).
//
RX   PubMed=20143388; DOI=10.1002/ijc.25242;
RA   Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A.,
RA   MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R.,
RA   Freshney R.I.;
RT   "Check your cultures! A list of cross-contaminated or misidentified
RT   cell lines.";
RL   Int. J. Cancer 127:1-8(2010).
//