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Cellosaurus HD-Mar-2 (CVCL_2247)

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Cell line name HD-Mar-2
Synonyms HD-MAR-2; HD-MAR 2; HD-MAR2; HD-Mar2
Accession CVCL_2247
Resource Identification Initiative To cite this cell line use: HD-Mar-2 (RRID:CVCL_2247)
Comments Problematic cell line: Misclassified. Originally thought to be a Hodgkin lymphoma cell line, but seems to be a T lymphoblastic lymphoma (PubMed=29533902).
Doubling time: ~50 hours (DSMZ=ACC-685).
Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
Cell type: T-cell; CL=CL_0000084.
Disease Adult T lymphoblastic lymphoma (NCIt: C7226)
T-cell non-Hodgkin lymphoma (ORDO: Orphanet_171918)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_B367 (HD-Mar)
Sex of cell Male
Age at sampling 20Y
Category Cancer cell line
STR profile Source(s): DSMZ=ACC-685; RCB=RCB1981; TKG=TKG 0198

Markers:
AmelogeninX,Y
CSF1PO6,10
D2S133816,21
D3S135815,16
D5S81811
D7S82010,12
D8S117914
D13S3178,13
D16S53913
D18S5116,18
D19S43314,15
D21S1130,31.2
FGA21,25
Penta D11
Penta E11,15
TH016,9.3
TPOX8
vWA16,17

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Publications

PubMed=2985879; DOI=10.1016/0145-2126(85)90084-0
Hans Gunther Drexler, Gerhard Gaedicke, Jun Minowada;
Isoenzyme studies in human leukemia-lymphoma cell lines -- 1 Carboxylic esterase.
Leuk. Res. 9:209-229(1985)

PubMed=3159941; DOI=10.1016/0145-2126(85)90134-1
Hans Gunther Drexler, Gerhard Gaedicke, Jun Minowada;
Isoenzyme studies in human leukemia-lymphoma cell lines -- III Beta-hexosaminidase (E.C. 3.2.1.30).
Leuk. Res. 9:549-559(1985)

PubMed=3874327; DOI=10.1016/0145-2126(85)90133-x
Hans Gunther Drexler, Gerhard Gaedicke, Jun Minowada;
Isoenzyme studies in human leukemia-lymphoma cells lines -- II. Acid phosphatase.
Leuk. Res. 9:537-548(1985)

PubMed=8127147
Mats Heyman, Dan Grander, Karen Brondum-Nielsen, Britta Cederblad, Yie Liu, Bo Xu, Stefan Einhorn;
Interferon system defects in malignant T-cells.
Leukemia 8:425-434(1994)

PubMed=8641406; DOI=10.1111/j.1600-0609.1996.tb00721.x
Laura Borgonovo-Brandter, Mats Heyman, Omid Rasool, Yie Liu, Dan Grander, Stefan Einhorn;
p16INK4/p15INK4B gene inactivation is a frequent event in malignant T-cell lines.
Eur. J. Haematol. 56:313-318(1996)

PubMed=29533902; DOI=10.1515/hsz-2017-0321
Hans Gunther Drexler, Claudia Pommerenke, Sonja Eberth, Stefan Nagel;
Hodgkin lymphoma cell lines: to separate the wheat from the chaff.
Biol. Chem. 399:511-523(2018)

Cross-references
Cell line collections (Providers) DSMZ; ACC-685
RCB; RCB1981
TKG; TKG 0198
Cell line databases/resources CLO; CLO_0050144
DSMZCellDive; ACC-685
Biological sample resources BioSample; SAMN03473438
Encyclopedic resources Wikidata; Q54882096
Gene expression databases FANTOM5_SSTAR; 10435-106E3
Polymorphism and mutation databases Cosmic; 933541
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number20