ID   HD-Mar-2
AC   CVCL_2247
SY   HD-MAR-2; HD-MAR 2; HD-MAR2; HD-Mar2
DR   CLO; CLO_0050144
DR   BioSample; SAMN03473438
DR   Cosmic; 933541
DR   DSMZ; ACC-685
DR   DSMZCellDive; ACC-685
DR   FANTOM5_SSTAR; 10435-106E3
DR   RCB; RCB1981
DR   TKG; TKG 0198
DR   Wikidata; Q54882096
RX   PubMed=2985879;
RX   PubMed=3159941;
RX   PubMed=3874327;
RX   PubMed=8127147;
RX   PubMed=8641406;
RX   PubMed=29533902;
CC   Problematic cell line: Misclassified. Originally thought to be a Hodgkin lymphoma cell line, but seems to be a T lymphoblastic lymphoma (PubMed=29533902).
CC   Doubling time: ~50 hours (DSMZ=ACC-685).
CC   Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
CC   Cell type: T-cell; CL=CL_0000084.
ST   Source(s): DSMZ=ACC-685; RCB=RCB1981; TKG=TKG 0198
ST   Amelogenin: X,Y
ST   CSF1PO: 6,10
ST   D13S317: 8,13
ST   D16S539: 13
ST   D18S51: 16,18
ST   D19S433: 14,15
ST   D21S11: 30,31.2
ST   D2S1338: 16,21
ST   D3S1358: 15,16
ST   D5S818: 11
ST   D7S820: 10,12
ST   D8S1179: 14
ST   FGA: 21,25
ST   Penta D: 11
ST   Penta E: 11,15
ST   TH01: 6,9.3
ST   TPOX: 8
ST   vWA: 16,17
DI   NCIt; C7226; Adult T lymphoblastic lymphoma
DI   ORDO; Orphanet_171918; T-cell non-Hodgkin lymphoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_B367 ! HD-Mar
SX   Male
AG   20Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 20
//
RX   PubMed=3159941; DOI=10.1016/0145-2126(85)90134-1;
RA   Drexler, Hans Gunther
RA   Gaedicke, Gerhard
RA   Minowada, Jun
RT   "Isoenzyme studies in human leukemia-lymphoma cell lines -- III.
RT   Beta-hexosaminidase (E.C. 3.2.1.30).";
RL   Leuk. Res. 9:549-559(1985).
//
RX   PubMed=8641406; DOI=10.1111/j.1600-0609.1996.tb00721.x;
RA   Borgonovo-Brandter, Laura
RA   Heyman, Mats
RA   Rasool, Omid
RA   Liu, Yie
RA   Grander, Dan
RA   Einhorn, Stefan
RT   "p16INK4/p15INK4B gene inactivation is a frequent event in malignant
RT   T-cell lines.";
RL   Eur. J. Haematol. 56:313-318(1996).
//
RX   PubMed=29533902; DOI=10.1515/hsz-2017-0321;
RA   Drexler, Hans Gunther
RA   Pommerenke, Claudia
RA   Eberth, Sonja
RA   Nagel, Stefan
RT   "Hodgkin lymphoma cell lines: to separate the wheat from the chaff.";
RL   Biol. Chem. 399:511-523(2018).
//
RX   PubMed=2985879; DOI=10.1016/0145-2126(85)90084-0;
RA   Drexler, Hans Gunther
RA   Gaedicke, Gerhard
RA   Minowada, Jun
RT   "Isoenzyme studies in human leukemia-lymphoma cell lines -- 1.
RT   Carboxylic esterase.";
RL   Leuk. Res. 9:209-229(1985).
//
RX   PubMed=3874327; DOI=10.1016/0145-2126(85)90133-x;
RA   Drexler, Hans Gunther
RA   Gaedicke, Gerhard
RA   Minowada, Jun
RT   "Isoenzyme studies in human leukemia-lymphoma cells lines -- II. Acid
RT   phosphatase.";
RL   Leuk. Res. 9:537-548(1985).
//
RX   PubMed=8127147;
RA   Heyman, Mats
RA   Grander, Dan
RA   Brondum-Nielsen, Karen
RA   Cederblad, Britta
RA   Liu, Yie
RA   Xu, Bo
RA   Einhorn, Stefan
RT   "Interferon system defects in malignant T-cells.";
RL   Leukemia 8:425-434(1994).
//