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Cellosaurus PNT1A (CVCL_2163)

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Cell line name PNT1A
Synonyms PNT1a; PNT-1A; PNT1-a; PNT1/A
Accession CVCL_2163
Resource Identification Initiative To cite this cell line use: PNT1A (RRID:CVCL_2163)
Comments Doubling time: 29.93 +- 1.29 hours (PubMed=21556542).
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) [pMK16].
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Derived from sampling site: Prostate; epithelium. Cell type=Epithelial cell.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_4804 (PNT1)
CVCL_JX33 (PNT1A serum free )
Sex of cell Male
Age at sampling 35Y
Category Transformed cell line
STR profile Source(s): PubMed=11416159


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PubMed=7558421; DOI=10.1002/ijc.2910620613
Degeorges A., Hoffschir F., Cussenot O., Gauville C., Le Duc A., Dutrillaux B., Calvo F.
Recurrent cytogenetic alterations of prostate carcinoma and amplification of c-myc or epidermal growth factor receptor in subclones of immortalized PNT1 human prostate epithelial cell line.
Int. J. Cancer 62:724-731(1995)

PubMed=21556542; DOI=10.3892/ijo.6.2.333
Berthon P., Cussenot O., Hopwood L., Leduc A., Maitland N.J.
Functional expression of SV40 in normal human prostatic epithelial and fibroblastic cells: differentiation pattern of nontumorigenic cell-lines.
Int. J. Oncol. 6:333-343(1995)

PubMed=11694337; DOI=10.1016/S0303-7207(01)00669-4
Avances C., Georget V., Terouanne B., Orio F. Jr., Cussenot O., Mottet N., Costa P., Sultan C.
Human prostatic cell line PNT1A, a useful tool for studying androgen receptor transcriptional activity and its differential subnuclear localization in the presence of androgens and antiandrogens.
Mol. Cell. Endocrinol. 184:13-24(2001)

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458
Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P., Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J., Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C., Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J., Haber D.A.
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)

Cell line collections ECACC; 95012614
Cell line databases/resources CLO; CLO_0008475
CLDB; cl3926
Anatomy/cell type resources BTO; BTO:0003068
Encyclopedic resources Wikidata; Q54947679
Gene expression databases GEO; GSM827411
GEO; GSM1374835
Entry history
Entry creation04-Apr-2012
Last entry update23-Jun-2022
Version number19