ID   PNT1A
AC   CVCL_2163
SY   PNT1a; PNT-1A; PNT1-a; PNT1/A
DR   BTO; BTO_0003068
DR   CLO; CLO_0008475
DR   CLDB; cl3926
DR   ChEMBL-Cells; CHEMBL4513117
DR   ChEMBL-Targets; CHEMBL4513131
DR   ECACC; 95012614
DR   GEO; GSM827411
DR   GEO; GSM1374835
DR   PubChem_Cell_line; CVCL_2163
DR   Wikidata; Q54947679
RX   PubMed=7558421;
RX   PubMed=11416159;
RX   PubMed=11694337;
RX   PubMed=20215515;
RX   PubMed=21556542;
CC   Doubling time: 25 hours (PubMed=7558421); 29.93 +- 1.29 hours (PubMed=21556542).
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=pMK16).
CC   Omics: Transcriptomics; Microarray.
CC   Omics: Variations; SNP array analysis.
CC   Derived from site: In situ; Prostate, epithelium; UBERON=UBERON_0000428.
CC   Cell type: Epithelial cell of prostate; CL=CL_0002231.
ST   Source(s): PubMed=11416159
ST   Amelogenin: X,Y
ST   D18S51: 16
ST   D21S11: 27,28
ST   D8S1179: 10,12
ST   FGA: 24
ST   TH01: 6
ST   vWA: 17,19
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_4804 ! PNT1
SX   Male
AG   35Y
CA   Transformed cell line
DT   Created: 04-04-12; Last updated: 27-11-25; Version: 28
CH   CVCL_JX33 ! PNT1A serum free
//
RX   PubMed=7558421; DOI=10.1002/ijc.2910620613;
RA   Degeorges, Armelle
RA   Hoffschir, Francoise
RA   Cussenot, Olivier
RA   Gauville, Christiane
RA   Le Duc, Alain
RA   Dutrillaux, Bernard
RA   Calvo, Fabien
RT   "Recurrent cytogenetic alterations of prostate carcinoma and
RT   amplification of c-myc or epidermal growth factor receptor in
RT   subclones of immortalized PNT1 human prostate epithelial cell line.";
RL   Int. J. Cancer 62:724-731(1995).
//
RX   PubMed=11416159; DOI=10.1073/pnas.121616198; PMCID=PMC35459;
RA   Masters, John R.W.
RA   Thomson, Jim A.
RA   Daly-Burns, Bernadette
RA   Reid, Yvonne A.
RA   Dirks, Wilhelm Gerhard
RA   Packer, Phil
RA   Toji, Lorraine Hellenga
RA   Ohno, Tadao
RA   Tanabe, Hideyuki
RA   Arlett, Colin Francis
RA   Kelland, Lloyd R.
RA   Harrison, Maureen
RA   Virmani, Arvind K.
RA   Ward, Timothy H.
RA   Ayres, Karen L.
RA   Debenham, Paul G.
RT   "Short tandem repeat profiling provides an international reference
RT   standard for human cell lines.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:8012-8017(2001).
//
RX   PubMed=21556542; DOI=10.3892/ijo.6.2.333;
RA   Berthon, Philippe
RA   Cussenot, Olivier
RA   Hopwood, Lucy
RA   Le Duc, Alain
RA   Maitland, Norman J.
RT   "Functional expression of SV40 in normal human prostatic epithelial
RT   and fibroblastic cells: differentiation pattern of nontumorigenic
RT   cell-lines.";
RL   Int. J. Oncol. 6:333-343(1995).
//
RX   PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662;
RA   Rothenberg, S. Michael
RA   Mohapatra, Gayatry
RA   Rivera, Miguel N.
RA   Winokur, Daniel
RA   Greninger, Patricia
RA   Nitta, Mai
RA   Sadow, Peter M.
RA   Sooriyakumar, Gaya
RA   Brannigan, Brian W.
RA   Ulman, Matthew J.
RA   Perera, Rushika M.
RA   Wang, Rui
RA   Tam, Angela
RA   Ma, Xiao-Jun
RA   Erlander, Mark
RA   Sgroi, Dennis C.
RA   Rocco, James W.
RA   Lingen, Mark W.
RA   Cohen, Ezra E.W.
RA   Louis, David Neil
RA   Settleman, Jeffrey
RA   Haber, Daniel Arie
RT   "A genome-wide screen for microdeletions reveals disruption of
RT   polarity complex genes in diverse human cancers.";
RL   Cancer Res. 70:2158-2164(2010).
//
RX   PubMed=11694337; DOI=10.1016/S0303-7207(01)00669-4;
RA   Avances, Christophe
RA   Georget, Virginie
RA   Terouanne, Beatrice
RA   Orio, Francesco Jr.
RA   Cussenot, Olivier
RA   Mottet, Nicolas
RA   Costa, Pierre
RA   Sultan, Charles
RT   "Human prostatic cell line PNT1A, a useful tool for studying androgen
RT   receptor transcriptional activity and its differential subnuclear
RT   localization in the presence of androgens and antiandrogens.";
RL   Mol. Cell. Endocrinol. 184:13-24(2001).
//