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Cellosaurus MH1C1 (CVCL_2114)

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Cell line name MH1C1
Synonyms MH1-C1; MH 1 C 1
Accession CVCL_2114
Resource Identification Initiative To cite this cell line use: MH1C1 (RRID:CVCL_2114)
Comments Characteristics: Produces albumin and secretes it into the culture medium (PubMed=4177659).
Characteristics: Derived from the transplantable Morris hepatoma 7795 (PubMed=4177659).
Doubling time: 1 week (PubMed=4177659); ~33-60 hours (DSMZ=ACC-106).
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Cell type: Epithelial cell; CL=CL_0000066.
Disease Rat hepatocellular carcinoma (NCIt: C60416)
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: Buffalo; RS=RS_0000163.
Category Cancer cell line
Publications

PubMed=4177659; DOI=10.1083/jcb.40.1.236; PMCID=PMC2107590
U. Ingrid Richardson, Armen Haig Tashjian Jr., Lawrence Levine;
Establishment of a clonal strain of hepatoma cells which secrete albumin.
J. Cell Biol. 40:236-247(1969)

PubMed=4194308; DOI=10.4049/jimmunol.105.2.396
Frederick Allen Rommel, Marvin B. Goldlust, Frank Carter Bancroft, Manfred Martin Mayer, Armen Haig Tashjian Jr.;
Synthesis of the ninth component of complement by a clonal strain of rat hepatoma cells.
J. Immunol. 105:396-403(1970)

PubMed=4399803; DOI=10.1007/BF02616132
Armen Haig Tashjian Jr., Frank Carter Bancroft, U. Ingrid Richardson, Marvin B. Goldlust, Frederick Allen Rommel, Peter Ofner;
Multiple differentiated functions in an unusual clonal strain of hepatoma cells.
In Vitro 6:32-45(1970)

PubMed=4327442; DOI=10.1016/0006-291X(71)90644-9
Armen Haig Tashjian Jr., Norma J. Barowsky, Diane K. Jensen;
Thyrotropin releasing hormone: direct evidence for stimulation of prolactin production by pituitary cells in culture.
Biochem. Biophys. Res. Commun. 43:516-523(1971)

PubMed=3431441; DOI=10.1016/s0076-6879(87)51006-0
Gretchen J. Darlington;
Liver cell lines.
Methods Enzymol. 151:19-38(1987)

PubMed=24386269; DOI=10.1371/journal.pone.0083751; PMCID=PMC3875483
Matthew G. Permenter, William E. Dennis, Thomas E. Sutto, David Adam Jackson, John A. Lewis, Jonathan D. Stallings;
Exposure to cobalt causes transcriptomic and proteomic changes in two rat liver derived cell lines.
PLoS ONE 8:e83751.1-e83751.11(2013)

Cross-references
Cell line collections (Providers) ATCC; CCL-144
BCRC; 60143
DSMZ; ACC-106
ECACC; 85112702 - Discontinued
ICLC; ATL98014
IZSLER; BS TCL 41
Cell line databases/resources CLO; CLO_0007707
CLO; CLO_0007709
CLDB; cl3474
CLDB; cl3475
CLDB; cl3476
CLDB; cl3477
CLDB; cl4918
DSMZCellDive; ACC-106
Anatomy/cell type resources BTO; BTO_0000220
Chemistry resources ChEMBL-Cells; CHEMBL3307375
ChEMBL-Targets; CHEMBL614349
PubChem_Cell_line; CVCL_2114
Encyclopedic resources Wikidata; Q54905527
Gene expression databases GEO; GSM1240490
GEO; GSM1240491
GEO; GSM1240492
GEO; GSM1240493
GEO; GSM1240494
GEO; GSM1240495
GEO; GSM1240496
GEO; GSM1240497
GEO; GSM1240498
GEO; GSM1240499
GEO; GSM1240500
GEO; GSM1240501
Entry history
Entry creation04-Apr-2012
Last entry update14-Aug-2025
Version number19