ID   MH1C1
AC   CVCL_2114
SY   MH1-C1; MH 1 C 1
DR   BTO; BTO_0000220
DR   CLO; CLO_0007707
DR   CLO; CLO_0007709
DR   CLDB; cl3474
DR   CLDB; cl3475
DR   CLDB; cl3476
DR   CLDB; cl3477
DR   CLDB; cl4918
DR   ATCC; CCL-144
DR   BCRC; 60143
DR   ChEMBL-Cells; CHEMBL3307375
DR   ChEMBL-Targets; CHEMBL614349
DR   DSMZ; ACC-106
DR   DSMZCellDive; ACC-106
DR   ECACC; 85112702
DR   GEO; GSM1240490
DR   GEO; GSM1240491
DR   GEO; GSM1240492
DR   GEO; GSM1240493
DR   GEO; GSM1240494
DR   GEO; GSM1240495
DR   GEO; GSM1240496
DR   GEO; GSM1240497
DR   GEO; GSM1240498
DR   GEO; GSM1240499
DR   GEO; GSM1240500
DR   GEO; GSM1240501
DR   ICLC; ATL98014
DR   IZSLER; BS TCL 41
DR   PubChem_Cell_line; CVCL_2114
DR   Wikidata; Q54905527
RX   PubMed=3431441;
RX   PubMed=4177659;
RX   PubMed=4194308;
RX   PubMed=4327442;
RX   PubMed=4399803;
RX   PubMed=24386269;
CC   Characteristics: Produces albumin and secretes it into the culture medium (PubMed=4177659).
CC   Characteristics: Derived from the transplantable Morris hepatoma 7795 (PubMed=4177659).
CC   Doubling time: 1 week (PubMed=4177659); ~33-60 hours (DSMZ=ACC-106).
CC   Omics: Transcriptomics; Microarray.
CC   Discontinued: ECACC; 85112702; probable.
CC   Derived from site: In situ; Liver; UBERON=UBERON_0002107.
CC   Cell type: Epithelial cell; CL=CL_0000066.
CC   Breed/subspecies: Buffalo; RS=RS_0000163.
DI   NCIt; C60416; Rat hepatocellular carcinoma
OX   NCBI_TaxID=10116; ! Rattus norvegicus (Rat)
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 18
//
RX   PubMed=3431441; DOI=10.1016/s0076-6879(87)51006-0;
RA   Darlington G.J.;
RT   "Liver cell lines.";
RL   Methods Enzymol. 151:19-38(1987).
//
RX   PubMed=4177659; DOI=10.1083/jcb.40.1.236; PMCID=PMC2107590;
RA   Richardson U.I., Tashjian A.H. Jr., Levine L.;
RT   "Establishment of a clonal strain of hepatoma cells which secrete
RT   albumin.";
RL   J. Cell Biol. 40:236-247(1969).
//
RX   PubMed=4194308; DOI=10.4049/jimmunol.105.2.396;
RA   Rommel F.A., Goldlust M.B., Bancroft F.C., Mayer M.M., Tashjian A.H. Jr.;
RT   "Synthesis of the ninth component of complement by a clonal strain of
RT   rat hepatoma cells.";
RL   J. Immunol. 105:396-403(1970).
//
RX   PubMed=4327442; DOI=10.1016/0006-291X(71)90644-9;
RA   Tashjian A.H. Jr., Barowsky N.J., Jensen D.K.;
RT   "Thyrotropin releasing hormone: direct evidence for stimulation of
RT   prolactin production by pituitary cells in culture.";
RL   Biochem. Biophys. Res. Commun. 43:516-523(1971).
//
RX   PubMed=4399803; DOI=10.1007/BF02616132;
RA   Tashjian A.H. Jr., Bancroft F.C., Richardson U.I., Goldlust M.B.,
RA   Rommel F.A., Ofner P.;
RT   "Multiple differentiated functions in an unusual clonal strain of
RT   hepatoma cells.";
RL   In Vitro 6:32-45(1970).
//
RX   PubMed=24386269; DOI=10.1371/journal.pone.0083751; PMCID=PMC3875483;
RA   Permenter M.G., Dennis W.E., Sutto T.E., Jackson D.A., Lewis J.A.,
RA   Stallings J.D.;
RT   "Exposure to cobalt causes transcriptomic and proteomic changes in two
RT   rat liver derived cell lines.";
RL   PLoS ONE 8:e83751.1-e83751.11(2013).
//