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Cellosaurus ELF-153 (CVCL_2031)

[Text version]
Cell line name ELF-153
Synonyms Elf-153; ELF153
Accession CVCL_2031
Resource Identification Initiative To cite this cell line use: ELF-153 (RRID:CVCL_2031)
Comments Part of: LL-100 blood cancer cell line panel.
Characteristics: CSF2 dependent.
Doubling time: 36 hours (PubMed=7488550; PubMed=7519473); ~40-60 hours (DSMZ=ACC-693).
Omics: Deep exome analysis.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
HLA typing Source: DSMZCellDive=ACC-693
Class I
HLA-AA*01:01:01,02:01:01
HLA-BB*08:01:01,35:01:01
HLA-CC*07:01:01,07:01:01
Class II
HLA-DPDPA1*01:03:01,02:01:01
DPB1*14:01:01,04:02:01
HLA-DQDQB1*03:01:01,03:01:01
HLA-DRDRA*01:01:01,01:01:01
DRB1*09:01:02,11:01:01
Disease Adult acute myeloid leukemia (NCIt: C9154)
Acute myeloid leukemia (ORDO: Orphanet_519)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 41Y
Category Cancer cell line
STR profile Source(s): DSMZ; Genomics_Center_BCF_Technion

Markers:
AmelogeninX
CSF1PO10
D1S165615.3,16
D2S44111,14
D2S133818,25
D3S135817,18 (Genomics_Center_BCF_Technion)
18 (DSMZ)
D5S81811
D7S8209,10 (DSMZ)
9.3 (Genomics_Center_BCF_Technion)
D8S117912,13
D10S124813,14
D12S39119
D13S3178
D16S53912,13
D18S5112,15
D19S43313,14.2 (Genomics_Center_BCF_Technion)
13,15 (DSMZ)
D21S1131,32.2
D22S104516
FGA19,23
Penta D12,13
Penta E12,14
TH016,9
TPOX8,11
vWA19

Run an STR similarity search on this cell line
Publications

CLPUB00037
Freund M., Kleine H.-D., Lux E., Exeriede G., Hanauske A.-R., Herbst H., Vainchenker W., Schweigerer L., Fonatsch C., Poliwoda H.
ELF-153: a novel cell line derived from a patient with acute myelofibrosis and AML.
Blut 61:128-128(1990)

PubMed=7519473; DOI=10.1182/blood.V84.4.1085.1085
Mouthon M.-A., Freund M., Titeux M., Katz A., Guichard J., Breton-Gorius J., Vainchenker W.
Growth and differentiation of the human megakaryoblastic cell line (ELF-153): a model for early stages of megakaryocytopoiesis.
Blood 84:1085-1097(1994)

PubMed=7488550
Hassan H.T., Hanauske A.-R., Lux E., Kleine H.-D., Freund M.
A new fibroblast growth stimulating activity from the human megakaryoblastic leukaemia cell line ELF-153: in vitro and in vivo findings.
Int. J. Exp. Pathol. 76:361-367(1995)

DOI=10.1016/B978-0-12-221970-2.50457-5
Drexler H.G.
The leukemia-lymphoma cell line factsbook.
(In) ISBN 9780122219702; pp.1-733; Academic Press; London (2001)

PubMed=16408098; DOI=10.1038/sj.leu.2404081
Quentmeier H., MacLeod R.A.F., Zaborski M., Drexler H.G.
JAK2 V617F tyrosine kinase mutation in cell lines derived from myeloproliferative disorders.
Leukemia 20:471-476(2006)

PubMed=31160637; DOI=10.1038/s41598-019-44491-x
Quentmeier H., Pommerenke C., Dirks W.G., Eberth S., Koeppel M., MacLeod R.A.F., Nagel S., Steube K., Uphoff C.C., Drexler H.G.
The LL-100 panel: 100 cell lines for blood cancer studies.
Sci. Rep. 9:8218-8218(2019)

Cross-references
Cell line collections (Providers) DSMZ; ACC-693
Cell line databases/resources DSMZCellDive; ACC-693
Biological sample resources BioSample; SAMN03473443
Encyclopedic resources Wikidata; Q54832241
Gene expression databases ArrayExpress; E-MTAB-7721
ArrayExpress; E-MTAB-7722
Polymorphism and mutation databases Cosmic; 787427
Cosmic; 975245
Cosmic; 1012064
Cosmic; 1281310
Cosmic; 1465954
Cosmic; 2306197
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number19