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Cellosaurus COR-L23/5010 (CVCL_2006)

[Text version]
Cell line name COR-L23/5010
Accession CVCL_2006
Resource Identification Initiative To cite this cell line use: COR-L23/5010 (RRID:CVCL_2006)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI:28748; Doxorubicin (Adriablastin; Adriamycin).
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012583; Zygosity=Homozygous (from parent cell line).
Disease Lung large cell carcinoma (NCIt: C4450)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1139 (COR-L23)
Sex of cell Male
Age at sampling 62Y
Category Cancer cell line
STR profile Source(s): ECACC

Markers:
AmelogeninX
CSF1PO11
D5S81810,12
D7S8209
D13S31710,11
D16S53911,13
TH019
TPOX8,11
vWA19

Run an STR similarity search on this cell line
Publications

PubMed=7903701; DOI=10.1093/jnci/86.2.110
Barrand M.A., Heppell-Parton A.C., Wright K.A., Rabbitts P.H., Twentyman P.R.
A 190-kilodalton protein overexpressed in non-P-glycoprotein-containing multidrug-resistant cells and its relationship to the MRP gene.
J. Natl. Cancer Inst. 86:110-117(1994)

Cross-references
Cell line collections (Providers) ECACC; 96042338
Cell line databases/resources CLO; CLO_0002586
CLDB; cl5054
cancercelllines; CVCL_2006
Encyclopedic resources Wikidata; Q54814271
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number17