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Cellosaurus DT40-PRKCB(-/-) (CVCL_1T42)

[Text version]
Cell line name DT40-PRKCB(-/-)
Synonyms PKCbeta^(-)DT40
Accession CVCL_1T42
Resource Identification Initiative To cite this cell line use: DT40-PRKCB(-/-) (RRID:CVCL_1T42)
Comments Group: Bird cell line.
Knockout cell: Method=Targeted integration; UniProtKB; Q5F3X1; PRKCB.
Transformant: NCBI_TaxID; 11864; Avian leukosis virus (ALV).
Cell type: B-cell; CL=CL_0000236.
Disease Chicken bursal lymphoma (NCIt: C134556)
Species of origin Gallus gallus (Chicken) (NCBI Taxonomy: 9031)
Breed/subspecies: Hy-Line SC.
Hierarchy Parent: CVCL_0249 (DT40)
Sex of cell Female
Age at sampling 1D
Category Cancer cell line

PubMed=16301747; DOI=10.1084/jem.20051591
Shinohara H., Yasuda T., Aiba Y., Sanjo H., Hamadate M., Watarai H., Sakurai H., Kurosaki T.
PKC beta regulates BCR-mediated IKK activation by facilitating the interaction between TAK1 and CARMA1.
J. Exp. Med. 202:1423-1431(2005)

Cell line collections (Providers) RCB; RCB2297
Cell line databases/resources CLO; CLO_0051526
Encyclopedic resources Wikidata; Q54831506
Entry history
Entry creation08-Jul-2015
Last entry update30-Jan-2024
Version number10