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Cellosaurus DT40-BLNK(-/-) (CVCL_1T38)

[Text version]
Cell line name DT40-BLNK(-/-)
Synonyms BLNK-/- DT40; BLNK^(-) DT40
Accession CVCL_1T38
Resource Identification Initiative To cite this cell line use: DT40-BLNK(-/-) (RRID:CVCL_1T38)
Comments Group: Bird cell line.
Knockout cell: Method=Targeted integration; UniProtKB; Q9YGC1; BLNK.
Transformant: NCBI_TaxID; 11864; Avian leukosis virus (ALV).
Cell type: B-cell; CL=CL_0000236.
Disease Chicken bursal lymphoma (NCIt: C134556)
Species of origin Gallus gallus (Chicken) (NCBI Taxonomy: 9031)
Breed/subspecies: Hy-Line SC.
Hierarchy Parent: CVCL_0249 (DT40)
CVCL_1T52 (DT40-BLNK(-/-)-SYK(-/-))
Sex of cell Female
Age at sampling 1D
Category Cancer cell line

PubMed=10023776; DOI=10.1016/S1074-7613(00)80012-6
Ishiai M., Kurosaki M., Pappu R., Okawa K., Ronko I., Fu C., Shibata M., Iwamatsu A., Chan A.C.-Y., Kurosaki T.
BLNK required for coupling Syk to PLC gamma 2 and Rac1-JNK in B cells.
Immunity 10:117-125(1999)

Cell line collections (Providers) RCB; RCB1510
Cell line databases/resources CLO; CLO_0051487
Encyclopedic resources Wikidata; Q54831474
Entry history
Entry creation08-Jul-2015
Last entry update30-Jan-2024
Version number10