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Cellosaurus NP-5 (CVCL_1R17)

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Cell line name NP-5
Synonyms NP 5; NP5; Case 5; NB4135
Accession CVCL_1R17
Resource Identification Initiative To cite this cell line use: NP-5 (RRID:CVCL_1R17)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Population: Japanese.
Omics: Genomics; Whole exome sequencing.
Derived from site: In situ; Brain, right parietal lobe; UBERON=UBERON_0002803.
Sequence variations
  • Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Arg233Ter (c.697C>T); ClinVar=VCV000007813; Zygosity=Unspecified (PubMed=10551321; DepMap=ACH-001610).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273Cys (c.817C>T); ClinVar=VCV000043594; Zygosity=Unspecified (PubMed=8878451; DepMap=ACH-001610).
Disease Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 27Y
Category Cancer cell line
STR profile Source(s): DepMap=ACH-001610; JCRB=JCRB1569

Markers:
AmelogeninX,Y
CSF1PO12
D3S135815
D5S81813
D7S82012,13
D8S117911,14
D13S3179
D16S53910,12
D18S5115,16
D21S1129,32.2
FGA20
Penta D9,10
Penta E14,15,22
TH019
TPOX8,11
vWA17

Run an STR similarity search on this cell line
Publications

PubMed=8878451; DOI=10.1111/j.1349-7006.1996.tb02118.x; PMCID=PMC5921198
Shu-Jing Zhang, Sumio Endo, Hisashi Koga, Tomio Ichikawa, Xue-Lian Feng, Kiyoshi Onda, Kazuo Washiyama, Toshiro Kumanishi;
A comparative study of glioma cell lines for p16, p15, p53 and p21 gene alterations.
Jpn. J. Cancer Res. 87:900-907(1996)

PubMed=10551321; DOI=10.1111/j.1349-7006.1999.tb00838.x; PMCID=PMC5926156
Shu-Jing Zhang, Sumio Endo, Tomio Ichikawa, Jun-ichi Yoshimura, Kiyoshi Onda, Ryuichi Tanaka, Kazuo Washiyama, Toshiro Kumanishi;
Rare-type mutations of MMAC1 tumor suppressor gene in human glioma cell lines and their tumors of origin.
Jpn. J. Cancer Res. 90:934-941(1999)

PubMed=18415661; DOI=10.1007/s10014-007-0226-0
Yoshiyuki Tanaka, Shu-Jing Zhang, Hiroshi Terasaki, Hisashi Koga, Sumio Endo, Hiroshi Usui, Kazuo Washiyama, Toshiro Kumanishi, Yuji Uematsu, Toru Itakura;
Frequent and variable abnormalities in p14 tumor suppressor gene in glioma cell lines.
Brain Tumor Pathol. 25:9-17(2008)

Cross-references
Cell line collections (Providers) JCRB; JCRB1569
RCB; RCB4505
Cell line databases/resources cancercelllines; CVCL_1R17
Cell_Model_Passport; SIDM01885
DepMap; ACH-001610
Encyclopedic resources Wikidata; Q54930958
Entry history
Entry creation08-Jul-2015
Last entry update10-Apr-2025
Version number19