ID   NP-5
AC   CVCL_1R17
SY   NP 5; NP5; Case 5; NB4135
DR   cancercelllines; CVCL_1R17
DR   Cell_Model_Passport; SIDM01885
DR   DepMap; ACH-001610
DR   JCRB; JCRB1569
DR   RCB; RCB4505
DR   Wikidata; Q54930958
RX   PubMed=8878451;
RX   PubMed=10551321;
RX   PubMed=18415661;
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Population: Japanese.
CC   Sequence variation: Mutation; HGNC; 9588; PTEN; Simple; p.Arg233Ter (c.697C>T); ClinVar=VCV000007813; Zygosity=Unspecified (PubMed=10551321; DepMap).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg273Cys (c.817C>T); ClinVar=VCV000043594; Zygosity=Unspecified (PubMed=8878451; DepMap).
CC   Omics: Deep exome analysis.
CC   Derived from site: In situ; Brain, right parietal lobe; UBERON=UBERON_0002803.
ST   Source(s): DepMap; JCRB
ST   Amelogenin: X,Y
ST   CSF1PO: 12
ST   D13S317: 9
ST   D16S539: 10,12
ST   D18S51: 15,16
ST   D21S11: 29,32.2
ST   D3S1358: 15
ST   D5S818: 13
ST   D7S820: 12,13
ST   D8S1179: 11,14
ST   FGA: 20
ST   Penta D: 9,10
ST   Penta E: 14,15,22
ST   TH01: 9
ST   TPOX: 8,11
ST   vWA: 17
DI   NCIt; C3058; Glioblastoma
DI   ORDO; Orphanet_360; Glioblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   27Y
CA   Cancer cell line
DT   Created: 08-07-15; Last updated: 05-10-23; Version: 16
//
RX   PubMed=8878451; DOI=10.1111/j.1349-7006.1996.tb02118.x;
RA   Zhang S., Endo S., Koga H., Ichikawa T., Feng X., Onda K.,
RA   Washiyama K., Kumanishi T.;
RT   "A comparative study of glioma cell lines for p16, p15, p53 and p21
RT   gene alterations.";
RL   Jpn. J. Cancer Res. 87:900-907(1996).
//
RX   PubMed=10551321; DOI=10.1111/j.1349-7006.1999.tb00838.x;
RA   Zhang S.-J., Endo S., Ichikawa T., Yoshimura J., Onda K., Tanaka R.,
RA   Washiyama K., Kumanishi T.;
RT   "Rare-type mutations of MMAC1 tumor suppressor gene in human glioma
RT   cell lines and their tumors of origin.";
RL   Jpn. J. Cancer Res. 90:934-941(1999).
//
RX   PubMed=18415661; DOI=10.1007/s10014-007-0226-0;
RA   Tanaka Y., Zhang S.-J., Terasaki H., Koga H., Endo S., Usui H.,
RA   Washiyama K., Kumanishi T., Uematsu Y., Itakura T.;
RT   "Frequent and variable abnormalities in p14 tumor suppressor gene in
RT   glioma cell lines.";
RL   Brain Tumor Pathol. 25:9-17(2008).
//