ID   NP-5
AC   CVCL_1R17
SY   NP 5; NP5; Case 5; NB4135
DR   cancercelllines; CVCL_1R17
DR   Cell_Model_Passport; SIDM01885
DR   DepMap; ACH-001610
DR   JCRB; JCRB1569
DR   RCB; RCB4505
DR   Wikidata; Q54930958
RX   PubMed=8878451;
RX   PubMed=10551321;
RX   PubMed=18415661;
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Population: Japanese.
CC   Sequence variation: Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Arg233Ter (c.697C>T); ClinVar=VCV000007813; Zygosity=Unspecified (PubMed=10551321; DepMap=ACH-001610).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273Cys (c.817C>T); ClinVar=VCV000043594; Zygosity=Unspecified (PubMed=8878451; DepMap=ACH-001610).
CC   Omics: Genomics; Whole exome sequencing.
CC   Derived from site: In situ; Brain, right parietal lobe; UBERON=UBERON_0002803.
ST   Source(s): DepMap=ACH-001610; JCRB=JCRB1569
ST   Amelogenin: X,Y
ST   CSF1PO: 12
ST   D13S317: 9
ST   D16S539: 10,12
ST   D18S51: 15,16
ST   D21S11: 29,32.2
ST   D3S1358: 15
ST   D5S818: 13
ST   D7S820: 12,13
ST   D8S1179: 11,14
ST   FGA: 20
ST   Penta D: 9,10
ST   Penta E: 14,15,22
ST   TH01: 9
ST   TPOX: 8,11
ST   vWA: 17
DI   NCIt; C3058; Glioblastoma
DI   ORDO; Orphanet_360; Glioblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   27Y
CA   Cancer cell line
DT   Created: 08-07-15; Last updated: 10-04-25; Version: 19
//
RX   PubMed=8878451; DOI=10.1111/j.1349-7006.1996.tb02118.x; PMCID=PMC5921198;
RA   Zhang, Shu-Jing
RA   Endo, Sumio
RA   Koga, Hisashi
RA   Ichikawa, Tomio
RA   Feng, Xue-Lian
RA   Onda, Kiyoshi
RA   Washiyama, Kazuo
RA   Kumanishi, Toshiro
RT   "A comparative study of glioma cell lines for p16, p15, p53 and p21
RT   gene alterations.";
RL   Jpn. J. Cancer Res. 87:900-907(1996).
//
RX   PubMed=18415661; DOI=10.1007/s10014-007-0226-0;
RA   Tanaka, Yoshiyuki
RA   Zhang, Shu-Jing
RA   Terasaki, Hiroshi
RA   Koga, Hisashi
RA   Endo, Sumio
RA   Usui, Hiroshi
RA   Washiyama, Kazuo
RA   Kumanishi, Toshiro
RA   Uematsu, Yuji
RA   Itakura, Toru
RT   "Frequent and variable abnormalities in p14 tumor suppressor gene in
RT   glioma cell lines.";
RL   Brain Tumor Pathol. 25:9-17(2008).
//
RX   PubMed=10551321; DOI=10.1111/j.1349-7006.1999.tb00838.x; PMCID=PMC5926156;
RA   Zhang, Shu-Jing
RA   Endo, Sumio
RA   Ichikawa, Tomio
RA   Yoshimura, Jun-ichi
RA   Onda, Kiyoshi
RA   Tanaka, Ryuichi
RA   Washiyama, Kazuo
RA   Kumanishi, Toshiro
RT   "Rare-type mutations of MMAC1 tumor suppressor gene in human glioma
RT   cell lines and their tumors of origin.";
RL   Jpn. J. Cancer Res. 90:934-941(1999).
//