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Cellosaurus HROC69 (CVCL_1G06)

[Text version]
Cell line name HROC69
Synonyms HROC69P
Accession CVCL_1G06
Resource Identification Initiative To cite this cell line use: HROC69 (RRID:CVCL_1G06)
Comments From: Linnebacher, Michael; University of Rostock; Rostock; Germany.
Population: Caucasian.
Microsatellite instability: Stable (MSS) (PubMed=25926053).
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Colon, ascending; UBERON=UBERON_0001156.
Sequence variations
HLA typing Source: Direct_author_submission
Class I
HLA-AA*26:01,33:01
HLA-BB*18:01,52:01
HLA-CC*12:02,12:03
Class II
HLA-DQDQB1*03:01,06:01
HLA-DRDRB1*11:04,15:02
Disease Colon adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_YD53 ! B-LCL-HROC69
CVCL_1G07 ! HROC69 T0 M2
Sex of cell Male
Age at sampling 62Y
Category Cancer cell line
STR profile Source(s): CLS=300828; PubMed=25926053; PubMed=27087592

Markers:
AmelogeninX,Y
CSF1PO10,11
D5S81812,13
D7S82010,12
D13S31711,12,13 (PubMed=25926053)
12 (CLS=300828; PubMed=27087592)
D16S53911,12 (CLS=300828; PubMed=27087592)
12,13 (PubMed=25926053)
D21S1129,33.2
TH017,9.3 (CLS=300828; PubMed=25926053)
7,10 (PubMed=27087592)
TPOX8,12
vWA17,19 (CLS=300828; PubMed=25926053)
17,20 (PubMed=27087592)

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Publications

PubMed=25926053; DOI=10.1038/ncomms8002
Enzo Medico, Mariangela Russo, Gabriele Picco, Carlotta Cancelliere, Emanuele Valtorta, Giorgio Corti, Michela Buscarino, Claudio Isella, Simona Lamba, Barbara Martinoglio, Silvio Veronese ...Show all 19 authors... , Salvatore Siena, Andrea Sartore-Bianchi, Marco Beccuti, Marcella Mottolese, Michael Linnebacher, Francesca Cordero, Federica Di Nicolantonio, Alberto Bardelli; Show fewer authors
The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets.
Nat. Commun. 6:7002.1-7002.10(2015)

PubMed=27087592; DOI=10.1038/srep24671; PMCID=PMC4834534
Florian Kuehn, Christina Susanne Mullins, Mathias Krohn, Christine Harnack, Robert Ramer, Oliver H. Kramer, Ernst Klar, Maja Huhns, Michael Linnebacher;
Establishment and characterization of HROC69 -- a Crohn s related colonic carcinoma cell line and its matched patient-derived xenograft.
Sci. Rep. 6:24671-24671(2016)

PubMed=31601052; DOI=10.3390/cancers11101520; PMCID=PMC6826890
Christina Susanne Mullins, Bianca Micheel, Stephanie Matschos, Matthias Leuchter, Florian Burtin, Mathias Krohn, Maja Huhns, Ernst Klar, Friedrich Prall, Michael Linnebacher;
Integrated biobanking and tumor model establishment of human colorectal carcinoma provides excellent tools for preclinical research.
Cancers (Basel) 11:1520.1-1520.18(2019)

Cross-references
Cell line collections (Providers) CLS; 300828
Cell line databases/resources cancercelllines; CVCL_1G06
Encyclopedic resources Wikidata; Q54895301
Gene expression databases GEO; GSM1448080
Polymorphism and mutation databases Cosmic; 2795028
Entry history
Entry creation08-Jul-2015
Last entry update10-Apr-2025
Version number23